ArticleInfection and immunity2011
LipA, a tyrosine and lipid phosphatase involved in the virulence of Listeria monocytogenes.
Article in Infection and immunity, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 31 citations in OpenAlex.
- Genomic characterization ofMicrobial genomics · 2025Article
- First Report of Septicaemic Listeriosis in a Loggerhead Sea Turtle (Animals : an open access journal from MDPI · 2022Article
- Co-Infection ofMicroorganisms · 2022Article
- Retrospective Use of Whole-Genome Sequencing Expands the Multicountry Outbreak Cluster ofInternational journal of genomics · 2021Article
- TheFrontiers in cellular and infection microbiology · 2021Article
- Highly Potent and SelectiveJournal of medicinal chemistry · 2020Article
- Article
- CD83 orchestrates immunity toward self and non-self in dendritic cells.JCI insight · 2019Article
- Transcriptome Analysis of Landrace Pig Subcutaneous Preadipocytes during Adipogenic Differentiation.Genes · 2019Article
- Structure-Based Design of MptpB Inhibitors That Reduce Multidrug-Resistant Mycobacterium tuberculosis Survival and Infection Burden in Vivo.Journal of medicinal chemistry · 2018Article
- Article
- Function of Macrophage and Parasite Phosphatases in Leishmaniasis.Frontiers in immunology · 2017Review
- Enoyl-Acyl Carrier Protein Reductase I (FabI) Is Essential for the Intracellular Growth of Listeria monocytogenes.Infection and immunity · 2016Article
- The tyrosine kinase BceF and the phosphotyrosine phosphatase BceD of Burkholderia contaminans are required for efficient invasion and epithelial disruption of a cystic fibrosis lung epithelial cell line.Infection and immunity · 2015Article
- Metabolic host responses to infection by intracellular bacterial pathogens.Frontiers in cellular and infection microbiology · 2013Review
- Contribution of a TANK-binding kinase 1-interferon (IFN) regulatory factor 7 pathway to IFN-γ-induced gene expression.Molecular and cellular biology · 2012Article
- Tyrosine phosphorylation and bacterial virulence.International journal of oral science · 2012Review
- Listeria monocytogenes tyrosine phosphatases affect wall teichoic acid composition and phage resistance.FEMS microbiology letters · 2012Article
- Illuminating the landscape of host-pathogen interactions with the bacterium Listeria monocytogenes.Proceedings of the National Academy of Sciences of the United States of America · 2011Review
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 2 countries.
Funding
Abstract
Intracellular bacterial pathogens manipulate host cell functions by producing enzymes that stimulate or antagonize signal transduction. The Listeria monocytogenes genome contains a gene, lmo1800, encoding a protein with a conserved motif of conventional tyrosine phosphatases. Here, we report that the lmo1800-encoded protein LipA is secreted by Listeria and displays tyrosine as well as lipid phosphatase activity in vitro. Bacteria lacking LipA are severely attenuated in virulence in vivo, thus revealing a so-far-undescribed enzymatic activity involved in Listeria infection.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.