ArticleJournal of consulting and clinical psychology2011
A marginal structural model analysis for loneliness: implications for intervention trials and clinical practice.
Article in Journal of consulting and clinical psychology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04414826 (Preliminary Efficacy of a One-Session Mindfulness Telehealth Intervention for Loneliness), which is not on this map. Cited by 65 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Preliminary Efficacy of a One-Session Mindfulness Telehealth Intervention for Loneliness
Who cites it
65 citing papers in PubMed.
- G-estimation of causal pathways in vocational rehabilitation for adults with psychotic disorders - a secondary analysis of a randomized trial.BMC psychiatry · 2021Trial
- Contours of a causal feedback mechanism between adaptive personality and psychosocial function in patients with personality disorders: a secondary analysis from a randomized clinical trial.BMC psychiatry · 2017Trial
- The Senior Connection: design and rationale of a randomized trial of peer companionship to reduce suicide risk in later life.Contemporary clinical trials · 2013Trial
- Rumination and depression in Chinese college students: the roles of loneliness and gender.BMC psychology · 2025Article
- The Longitudinal Relationship of Loneliness With Frequency and Problematic Use of Alcohol and Cannabis Among Young Adults.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2025Article
- Vaping transitions and incident depressive symptoms among young adults: a marginal structural model analysis.American journal of epidemiology · 2025Article
- "I'm Trying to Reach Out, I'm Trying to Find My People": A Mixed-Methods Investigation of the Link Between Sensory Differences, Loneliness, and Mental Health in Autistic and Nonautistic Adults.Autism in adulthood · 2024Article
- The silent epidemic: exploring the link between loneliness and chronic diseases in China's elderly.BMC geriatrics · 2024Article
- Chronic loneliness and the risk of incident stroke in middle and late adulthood: a longitudinal cohort study of U.S. older adults.EClinicalMedicine · 2024Article
- Effectiveness of a Web-based and Mobile Therapy Chatbot on Anxiety and Depressive Symptoms in Subclinical Young Adults: Randomized Controlled Trial.JMIR formative research · 2024Article
- High-dimensional generalized median adaptive lasso with application to omics data.Briefings in bioinformatics · 2024Article
- Labor Market Consequences of Grandparenthood.Sociological science · 2024Article
- Instrumental Variable Estimation of Marginal Structural Mean Models for Time-Varying Treatment.Journal of the American Statistical Association · 2024Article
- A Short-Form Measure of Loneliness to Predict Depression Symptoms Among Adolescents.Child psychiatry and human development · 2023Article
- Trajectories of loneliness during COVID-19 pandemic and associations with mental health and substance use.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2023Article
- A Biopsychosocial Model Predicting Myocardial Infarction.Journal of clinical medicine · 2023Article
- First-line opioid agonist treatment as prevention against assisting others in initiating injection drug use: A longitudinal cohort study of people who inject drugs in Vancouver, Canada.Drug and alcohol dependence reports · 2023Article
- Association of loneliness and social isolation with all-cause mortality among older Mexican adults in the Mexican health and aging study: a retrospective observational study.BMC geriatrics · 2023Observational
- The gender dimensions of mental health during the Covid-19 pandemic: A path analysis.PloS one · 2023Article
- Relationships between Loneliness and Occupational Dysfunction in Community-Dwelling Older Adults: A Cross-Sectional Study.Occupational therapy international · 2023Article
5 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
objectiveClinical scientists, policymakers, and individuals must make decisions concerning effective interventions that address health-related issues. We use longitudinal data on loneliness and depressive symptoms and a new class of causal models to illustrate how empirical evidence can be used to inform intervention trial design and clinical practice.
methodData were obtained from a population-based study of non-Hispanic Caucasians, African Americans, and Latino Americans (N = 229) born between 1935 and 1952. Loneliness and depressive symptoms were measured with the UCLA Loneliness Scale-Revised and Center for Epidemiologic Studies Depression Scale, respectively. Marginal structural causal models were employed to evaluate the extent to which depressive symptoms depend not only on loneliness measured at a single point in time (as in prior studies of the effect of loneliness) but also on an individual's entire loneliness history.
resultsOur results indicate that if interventions to reduce loneliness by 1 standard deviation were made 1 and 2 years prior to assessing depressive symptoms, both would have an effect; together, they would result in an average reduction in depressive symptoms of 0.33 standard deviations, 95% CI [0.21, 0.44], p < .0001.
conclusionsThe magnitude and persistence of these effects suggest that greater effort should be devoted to developing practical interventions on alleviating loneliness and that doing so could be useful in the treatment and prevention of depressive symptoms. In light of the persistence of the effects of loneliness, our results also suggest that, in the evaluation of interventions on loneliness, it may be important to allow for a considerable follow-up period in assessing outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.