ArticleTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik2011
Positional cloning of ds1, the target leaf spot resistance gene against Bipolaris sorghicola in sorghum.
Article in TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 38 citations in OpenAlex.
- Plant Immunity: At the Crossroads of Pathogen Perception and Defense Response.Plants (Basel, Switzerland) · 2024Review
- NB-LRR-encoding genes conferring susceptibility to organophosphate pesticides in sorghum.Scientific reports · 2021Article
- Genome-wide association analysis of the strength of the MAMP-elicited defense response and resistance to target leaf spot in sorghum.Scientific reports · 2020Article
- QTG-Finder2: A Generalized Machine-Learning Algorithm for Prioritizing QTL Causal Genes in Plants.G3 (Bethesda, Md.) · 2020Article
- Identification of QTL for Target Leaf Spot resistance in Sorghum bicolor and investigation of relationships between disease resistance and variation in the MAMP response.Scientific reports · 2019Article
- Identification of a locus in maize controlling response to a host-selective toxin derived from Cochliobolus heterostrophus, causal agent of southern leaf blight.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2018Article
- The genome sequence of Bipolaris cookei reveals mechanisms of pathogenesis underlying target leaf spot of sorghum.Scientific reports · 2017Article
- Receptor Kinases in Plant-Pathogen Interactions: More Than Pattern Recognition.The Plant cell · 2017Review
- The Sorghum Gene for Leaf Color Changes upon Wounding (P) Encodes a Flavanone 4-Reductase in the 3-Deoxyanthocyanidin Biosynthesis Pathway.G3 (Bethesda, Md.) · 2016Article
- Expression ofFrontiers in plant science · 2016Article
- Expression level of a flavonoid 3'-hydroxylase gene determines pathogen-induced color variation in sorghum.BMC research notes · 2014Article
- Article
- Global transcriptome analysis reveals distinct expression among duplicated genes during sorghum-interaction.BMC plant biology · 2012Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Target leaf spot is one of the major sorghum diseases in southern Japan and caused by a necrotrophic fungus, Bipolaris sorghicola. Sorghum resistance to target leaf spot is controlled by a single recessive gene (ds1). A high-density genetic map of the ds1 locus was constructed with simple sequence repeat markers using progeny from crosses between a sensitive variety, bmr-6, and a resistant one, SIL-05, which allowed the ds1 gene to be genetically located within a 26-kb region on the short arm of sorghum chromosome 5. The sorghum genome annotation database for BTx623, for which the whole genome sequence was recently published, indicated a candidate gene from the Leucine-Rich Repeat Receptor Kinase family in this region. The candidate protein kinase gene was expressed in susceptible plants but was not expressed or was severely reduced in resistant plants. The expression patterns of ds1 gene and the phenotype of target leaf spot resistance were clearly correlated. Genomic sequences of this region in parental varieties showed a deletion in the promoter region of SIL-05 that could cause reduction of gene expression. We also found two ds1 alleles for resistant phenotypes with a stop codon in the coding region. The results shown here strongly suggest that the loss of function or suppression of the ds1 protein kinase gene leads to resistance to target leaf spot in sorghum.
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