Evidence map›Paper›PMID 21441474›Full record

ReviewAdvances in dental research2011

Virus-host interactions in HIV pathogenesis: directions for therapy.

J A Levy

Abstract readReview
In one paragraph

Review in Advances in dental research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
  3. TheFuture virology · 2020
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Human Immunodeficiency Virus (HIV).Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2016
    Article
  9. Review
  10. Article
  11. Article
  12. Natural antimicrobial peptides as promising anti-HIV candidates.Current topics in peptide & protein research
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

J A LevyDirector, Laboratory for Tumor and AIDS Virus Research, University of California, San Francisco, San Francisco, CA 94143-1270, USA. Jay.Levy@ucsf.edu

Funding

Role of Innate Immunity in Controlling HIV InfectionR01AI056992 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LEVY, JAY A · 2003 to 2010
$4.2M
NIAID NIH HHS 5R01AI056992-02NIAID NIH HHS R01 AI056992
6 · The paper itself

Abstract

The challenge of controlling HIV infection involves an understanding of the heterogeneity of the virus, its wide cellular host range, its primary routes of transmission, and the immunologic and intrinsic cellular factors that can prevent its transmission and replication. Identification of HIV-infected individuals who have survived more than 10 years without signs of the infection and without therapy encourages studies examining the natural mechanisms for resistance to infection and disease. Within the immune system, emphasis should be given to the innate or natural response that appears within minutes of the infection and offers the optimal time for controlling HIV. All these parameters in HIV pathogenesis underline the information needed to develop optimal anti-HIV therapies and an effective AIDS vaccine.

Indexed as

Antibodies, BlockingCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesHIV-1HIV InfectionsHIV Long-Term SurvivorsHost-Pathogen InteractionsHumansImmunity, InnateMacrophagesVirus InternalizationVirus ReplicationAntibodies, Blocking

Identifiers

PMID21441474
PMCPMC3144039

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.