ArticleLearning & memory (Cold Spring Harbor, N.Y.)2011
Second-order conditioning in Drosophila.
Article in Learning & memory (Cold Spring Harbor, N.Y.), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Profiling mouse behavior with computational tools to assess age-dependent differences in associative learning.Cell reports methods · 2025Article
- Article
- Resolving transitions between distinct phases of memory consolidation at high resolution iniScience · 2024Article
- Parabrachial Calca neurons mediate second-order conditioning.Nature communications · 2024Article
- Goal-directed behavior in Tenebrio molitor larvae.Scientific reports · 2024Article
- Diverse memory paradigms inLearning & memory (Cold Spring Harbor, N.Y.) · 2024Review
- Cognitive limits of larvalLearning & memory (Cold Spring Harbor, N.Y.) · 2024Article
- Roles of feedback and feed-forward networks of dopamine subsystems: insights fromLearning & memory (Cold Spring Harbor, N.Y.) · 2024Review
- Prediction error drives associative learning and conditioned behavior in a spiking model of Drosophila larva.iScience · 2024Article
- Article
- Minimal circuit motifs for second-order conditioning in the insect mushroom body.Frontiers in physiology · 2023Article
- Article
- Understanding Associative Learning Through Higher-Order Conditioning.Frontiers in behavioral neuroscience · 2022Review
- Learning with reinforcement prediction errors in a model of the Drosophila mushroom body.Nature communications · 2021Article
- Second-Order Conditioning in Humans.Frontiers in behavioral neuroscience · 2021Review
- Article
- Unlimited Associative Learning and the origins of consciousness: a primer and some predictions.Biology & philosophy · 2020Article
- Recurrent architecture for adaptive regulation of learning in the insect brain.Nature neuroscience · 2020Article
- An optogenetic analogue of second-order reinforcement in Drosophila.Biology letters · 2019Article
- Application of a Prediction Error Theory to Pavlovian Conditioning in an Insect.Frontiers in psychology · 2018Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Associative conditioning in Drosophila melanogaster has been well documented for several decades. However, most studies report only simple associations of conditioned stimuli (CS, e.g., odor) with unconditioned stimuli (US, e.g., electric shock) to measure learning or establish memory. Here we describe a straightforward second-order conditioning (SOC) protocol that further demonstrates the flexibility of fly behavior. In SOC, a previously conditioned stimulus (CS1) is used as reinforcement for a second conditioned stimulus (CS2) in associative learning. This higher-order context presents an opportunity for reassessing the roles of known learning and memory genes and neuronal networks in a new behavioral paradigm.
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