Evidence map›Paper›PMID 21441021›Full record

ReviewCurrent opinion in neurobiology2011

Understanding the functional consequences of synaptic specialization: insight from the Drosophila antennal lobe.

Rachel I Wilson

Abstract readReview
In one paragraph

Review in Current opinion in neurobiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Neuronal Network Models for Sensory Discrimination.Conference record. Asilomar Conference on Signals, Systems & Computers · 2016
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Parallel processing in the honeybee olfactory pathway: structure, function, and evolution.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2013
    Review
  14. Glutamate is an inhibitory neurotransmitter in the Drosophila olfactory system.Proceedings of the National Academy of Sciences of the United States of America · 2013
    Article
  15. Parallel processing via a dual olfactory pathway in the honeybee.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013
    Article
  16. Article
  17. Plasticity of recurrent inhibition in the Drosophila antennal lobe.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012
    Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Rachel I WilsonDepartment of Neurobiology, Harvard Medical School, 220 Longwood Ave., Boston, MA 02115, United States. rachel_wilson@hms.harvard.edu

Funding

Synaptic and Circuit Mechanisms of Olfactory ProcessingR01DC008174 · NIDCD · HARVARD MEDICAL SCHOOL · PI WILSON, RACHEL · 2006 to 2021
$5.5M
Howard Hughes Medical InstituteNIDCD NIH HHS R01 DC008174
6 · The paper itself

Abstract

Synapses exhibit diverse functional properties, and it seems likely that these properties are specialized to perform specific computations. The Drosophila antennal lobe provides a useful experimental preparation for exploring the relationship between synaptic physiology and neural computations. This review summarizes recent progress in describing synaptic properties in the Drosophila antennal lobe. These studies reveal that several types of synapses in this circuit are highly specialized, and that these specializations are in some cases under tight regulatory control. These synaptic specializations can be understood in terms of the computational features they confer on the circuit. Specifically, many of these properties appear to promote odor detection when odor concentrations are low, while promoting adaptive gain control when odor concentrations are high.

Indexed as

AnimalsArthropod AntennaeBrainDrosophilaSynapses

Identifiers

PMID21441021
PMCPMC3092845

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.