Evidence map›Paper›PMID 21440999›Full record

Trial reportDrug and alcohol dependence2011

Contingency management is efficacious and improves outcomes in cocaine patients with pretreatment marijuana use.

Sheila M Alessi, Carla Rash, Nancy M Petry

Open access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Drug and alcohol dependence, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 5 pooled it
3.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 5 syntheses or guidelines pooled it, 40 citations in OpenAlex.

  1. Pooled it
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  5. Pharmacological interventions for drug-using offenders.The Cochrane database of systematic reviews · 2015
    Pooled it
  6. Trial
  7. Trial
  8. Trial
  9. The impact of marijuana use on cocaine use outcomes among patients in methadone maintenance treatment across five trials of contingency management.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2022
    Article
  10. Article
  11. Article
  12. Co-use of Alcohol and Cannabis: A Review.Current addiction reports · 2017
    Article
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  14. Article
  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sheila M AlessiUniversity of Connecticut Health Center, Calhoun Cardiology Center - Behavioral Health, 263 Farmington Avenue, Farmington, CT 06030-3944, USA. salessi@uchc.edu
Carla Rash
Nancy M Petry
UConn Health · US

Funding

TSF to enhance treatment of cocaine dependenceP50DA009241 · NIDA · YALE UNIVERSITY · PI PETRY, NANCY M · 1994 to 2018
$40.5M
ZONISAMIDE VERSUS PLACEBOM01RR006192 · NCRR · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI KRANZLER, HENRY RICHARD · 1994 to 2008
$22.1M
Vulnerabilities for coping-related drinking among post-college young adultsP60AA003510 · NIAAA · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI PETRY, NANCY M · 2008 to 2017
$17.5M
VOUCHERS VS PRIZES--CONTINGENCY MANAGEMENTR01DA013444 · NIDA · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI ALESSI, SHEILA MARIE · 2000 to 2015
$6.2M
POST-DOCTORAL TRAINING PROGRAM IN ALCOHOL STUDIEST32AA007290 · NIAAA · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI SHEILA MARIE ALESSI · 1985 to 2026
$3.2M
Reinforcing Exercise in Cocaine AbusersR01DA027615 · NIDA · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI PETRY, NANCY M · 2009 to 2013
$3.2M
Contingency Management for Initiating Smoking AbstinenceR01DA024667 · NIDA · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI WHITE, WILLIAM BARRY · 2008 to 2012
$2.8M
Brief Therapies for Problem Gambling Substance AbusersR01DA021567 · NIDA · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI PETRY, NANCY M · 2007 to 2012
$2.7M
Group-Based Contingency Management/Outpatient TreatmentR01DA018883 · NIDA · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI PETRY, NANCY M · 2004 to 2008
$2.0M
Recovery Enhancement With Awards Enhancement With Awards Research Dissemination (P30DA023918 · NIDA · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI PETRY, NANCY M · 2009 to 2010
$1.8M
Training Therapists to Administer Contingency ManagementR01DA016855 · NIDA · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI PETRY, NANCY M · 2003 to 2007
$1.8M
Lower-Cost Contingency Management in a Group SettingR01DA014618 · NIDA · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI PETRY, NANCY M · 2002 to 2005
$1.4M
NCRR NIH HHS M01-RR06192NIAAA NIH HHS P60 AA003510NIAAA NIH HHS P60-AA03510NIAAA NIH HHS T32-AA07290NIDA NIH HHS P30 DA023918NIDA NIH HHS P30-DA023918NIDA NIH HHS P50 DA009241NIDA NIH HHS P50-DA09241NIDA NIH HHS R01 DA013444NIDA NIH HHS R01 DA014618NIDA NIH HHS R01 DA016855NIDA NIH HHS R01-DA016855NIDA NIH HHS R01 DA018883NIDA NIH HHS R01-DA018883NIDA NIH HHS R01-DA021567NIDA NIH HHS R01 DA022739NIDA NIH HHS R01-DA022739NIDA NIH HHS R01 DA024667NIDA NIH HHS R01-DA024667NIDA NIH HHS R01 DA027615NIDA NIH HHS R01-DA027615NIDA NIH HHS R01-DA13444NIDA NIH HHS R01-DA14618NIDA NIH HHS R21 DA021836NIDA NIH HHS R21-DA021836
6 · The paper itself

Abstract

backgroundMarijuana use is common in patients seeking treatment for cocaine use. Nevertheless, few studies have examined effects of marijuana use on treatment outcomes in general, and even fewer with respect to contingency management (CM) treatment, which has been criticized for potentially increasing non-reinforced drug use.

methodsData from three randomized clinical trials of CM versus standard treatment (ST) in cocaine-abusing patients were examined (Petry et al., 2004, 2005a, 2006a; N=393) to assess effects of pretreatment marijuana use on outcomes. Patients were divided into two groups: (1) no self-reported marijuana use (No Pre-M; n=315) and (2) any self-reported marijuana use (Pre-M; n=78) in the 30 days pretreatment.

resultsCM was especially efficacious in enhancing retention in Pre-M patients such that retention nearly doubled among Pre-M patients assigned to CM versus those assigned to ST. In contrast, CM exerted only modest benefits on retention in No Pre-M patients. Pretreatment marijuana use was not related to during-treatment abstinence from cocaine, opioids, and alcohol, or abstinence at a Month 9 follow-up. However, CM treatment and longest duration of abstinence achieved during treatment were significant predictors of Month 9 abstinence. Pre-M patients also evidenced more improvements in drug problems over time when randomized to CM.

conclusionsCM was especially efficacious in facilitating retention and improving severity of drug-related problems in those who used marijuana in the month before initiating treatment.

Indexed as

Substance Abuse DetectionAdultAmbulatory CareBehavior TherapyCentral Nervous System StimulantsCocaineCocaine-Related DisordersFemaleFollow-Up StudiesHumansMaleMarijuana SmokingPsychiatric Status Rating ScalesReinforcement, PsychologySubstance-Related DisordersTime FactorsCentral Nervous System StimulantsCocaine

Identifiers

PMID21440999
PMCPMC3143207
OpenAlexW1991851680

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.