ReviewBiochimica et biophysica acta2012
Methodologies for the characterization, identification and quantification of S-nitrosylated proteins.
Review in Biochimica et biophysica acta, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 37 citations in OpenAlex.
- The evolution of S-nitrosylation detection methodology and the role of protein S-nitrosylation in various cancers.Cancer cell international · 2024Review
- Protein S-Nitrosylation: A Chemical Modification with Ubiquitous Biological Activities.The protein journal · 2024Review
- Post-Translational S-Nitrosylation of Proteins in Regulating Cardiac Oxidative Stress.Antioxidants (Basel, Switzerland) · 2020Review
- Precision Profiling of the Cardiovascular Post-Translationally Modified Proteome: Where There Is a Will, There Is a Way.Circulation research · 2018Review
- Detection of ProteinBio-protocol · 2017Article
- Nitrosothiol-Trapping-Based Proteomic Analysis of S-Nitrosylation in Human Lung Carcinoma Cells.PloS one · 2017Article
- Harnessing Redox Cross-Reactivity To Profile Distinct Cysteine Modifications.Journal of the American Chemical Society · 2016Article
- S-Nitrosylation in neurogenesis and neuronal development.Biochimica et biophysica acta · 2015Review
- Reactive nitrogen species and hydrogen sulfide as regulators of protein tyrosine phosphatase activity.Antioxidants & redox signaling · 2014Review
- Monitoring in vivo reversible cysteine oxidation in proteins using ICAT and mass spectrometry.Nature protocols · 2014Article
- Resin-assisted enrichment of thiols as a general strategy for proteomic profiling of cysteine-based reversible modifications.Nature protocols · 2014Article
- Protein S-nitrosylation: specificity and identification strategies in plants.Frontiers in chemistry · 2014Review
- Direct methods for detection of protein S-nitrosylation.Methods (San Diego, Calif.) · 2013Review
- S-nitrosothiols and the S-nitrosoproteome of the cardiovascular system.Antioxidants & redox signaling · 2013Review
- Nitric oxide-based protein modification: formation and site-specificity of protein S-nitrosylation.Frontiers in plant science · 2013Article
- Superoxide dismutase as a novel macromolecular nitric oxide carrier: preparation and characterization.International journal of molecular sciences · 2012Article
- Measurement of S-nitrosylation occupancy in the myocardium with cysteine-reactive tandem mass tags: short communication.Circulation research · 2012Article
- Chasing cysteine oxidative modifications: proteomic tools for characterizing cysteine redox status.Circulation. Cardiovascular genetics · 2012Article
- S-nitrosylation: a radical way to protect the heart.Journal of molecular and cellular cardiology · 2012Review
- Identification and quantification of S-nitrosylation by cysteine reactive tandem mass tag switch assay.Molecular & cellular proteomics : MCP · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
backgroundProtein S-nitrosylation plays a central role in signal transduction by nitric oxide (NO), and aberrant S-nitrosylation of specific proteins is increasingly implicated in disease. SCOPE OF REVIEW: Here, methodologies for the characterization, identification and quantification of SNO-proteins are reviewed, focusing on techniques suitable for the structural characterization and absolute quantification of isolated SNO-proteins, the identification and relative quantification of SNO-proteins from complex mixtures as well as the mass spectrometry-based identification and relative quantification of sites of S-nitrosylation (SNO-sites) in proteins. MAJOR
conclusionsStructural characterization of SNO-proteins by X-ray crystallography is increasingly being utilized to understand both the relationships between protein structure and Cys thiol reactivity as well as the consequences of S-nitrosylation on protein structure and function. New methods for the proteomic identification and quantification of SNO-proteins and SNO-sites have greatly impacted the ability to study protein S-nitrosylation in complex biological systems. GENERAL SIGNIFICANCE: The ability to identify and quantify SNO-proteins has long been rate-determining for scientific advances in the field of protein S-nitrosylation. Therefore, it is critical that investigators in the field have a good understand the utility and limitations of modern analytical techniques for SNO-protein analysis. This article is part of a Special Issue entitled: Regulation of cellular processes by S-nitrosylation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.