ArticleColloids and surfaces. B, Biointerfaces2011
Thermodynamics of monolayers formed by mixtures of phosphatidylcholine/phosphatidylserine.
Article in Colloids and surfaces. B, Biointerfaces, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Programming Nonlinear Interfacial Mechanics of Synthetic Cells: Lipid Geometry and DNA Nanostructures.Small science · 2026Article
- Deciphering Lipid Arrangement in Phosphatidylserine/Phosphatidylcholine Mixed Membranes: Simulations and Experiments.Langmuir : the ACS journal of surfaces and colloids · 2023Article
- The Equilibria in Lipid-Lipoic Acid Systems: Monolayers, Microelectrophoretic and Interfacial Tension Studies.Molecules (Basel, Switzerland) · 2020Article
- Cations induce shape remodeling of negatively charged phospholipid membranes.Physical chemistry chemical physics : PCCP · 2017Article
- Material properties of matrix lipids determine the conformation and intermolecular reactivity of diacetylenic phosphatidylcholine in the lipid bilayer.Langmuir : the ACS journal of surfaces and colloids · 2011Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
In this work we obtain the thermodynamic properties of mixed (1-stearoyl-2-oleoyl-sn-glycero-3-phosphocholine) PC and (1-stearoyl-2-oleoyl-sn-glycero-3-phospho-l-serine (sodium salt)) PS monolayers. Measurements of compressibility (isotherms, bulk modulus, and excess area per molecule) and surface potential show that the properties of monolayers at the air-water interface depend on the concentration of ions (Na(+) and K(+)) and the proportion of PS in the mixture. The dependence on PS arises because the molecule is originally bound to a Na(+) counterion; by increasing the concentration of ions the entropy changes, creating a favorable system for the bound counterions of PS to join the bulk, leaving a negatively charged molecule. This change leads to an increase in electrostatic repulsions which is reflected by the increase in area per molecule versus surface pressure and a higher surface potential. The results lead to the conclusion that this mixture of phospholipids follows a non ideal behavior and can help to understand the thermodynamic behavior of membranes made of binary mixtures of a zwitterionic and an anionic phospholipid with a bound counterion.
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