ArticleJournal of the American Association for Laboratory Animal Science : JAALAS2011
Recovery from and clearance of rabies virus in a domestic ferret.
Article in Journal of the American Association for Laboratory Animal Science : JAALAS, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Incubation periods and mortality outcomes following rabies virus infection in mesocarnivorous reservoir hosts: implications for experimental design and veterinary policy - a review and meta-analysis.Virology journal · 2025Pooled it
- Rabies virus-neutralising antibodies in healthy, unvaccinated individuals: What do they mean for rabies epidemiology?PLoS neglected tropical diseases · 2020Review
- Article
- Virology, immunology and pathology of human rabies during treatment.The Pediatric infectious disease journal · 2015Article
- Ferret models of viral pathogenesis.Virology · 2015Review
- Differential Host Immune Responses after Infection with Wild-Type or Lab-Attenuated Rabies Viruses in Dogs.PLoS neglected tropical diseases · 2015Article
- Survival of rabid rabbits after intrathecal immunization.Neuropathology : official journal of the Japanese Society of Neuropathology · 2014Article
- Presence of virus neutralizing antibodies in cerebral spinal fluid correlates with non-lethal rabies in dogs.PLoS neglected tropical diseases · 2013Article
- Rabies: still a uniformly fatal disease? Historical occurrence, epidemiological trends, and paradigm shifts.Current infectious disease reports · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Here we document the case of a domestic ferret (Mustela putorius) that survived experimental inoculation with rabies virus of skunk origin. The ferret showed initial clinical signs of rabies (hindlimb paralysis) on day 81 after inoculation. The animal survived with paraplegia but otherwise was in an adequate nutritional state until the end of the observation period (PI day 181). At necropsy, no gross lesions were observed. Microscopic lesions were found in sections of cerebrum and spinal cord. In both tissues, the lesions were similar but were more severe with loss of neuronal parenchyma in the spinal cord. The lesions consisted of locally extensive areas with proliferation of astrocytes and moderate numbers of glial cells. Severely affected areas also contained clearly defined vacuoles in the neuropil. Multifocal areas of involvement showed mononuclear cuffing of blood vessels. In a few areas, the cuffing extended to the meninges. Rabies virus antigen was not detected by immunohistochemistry of tissue sections.
Indexed as
Identifiers
21439220PMC3061427W41768743What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.