ArticleChinese medicine2011
Myofascial trigger points: spontaneous electrical activity and its consequences for pain induction and propagation.
Article in Chinese medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 53 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Changes in Muscle Activity, Squat, and Gait Kinematics After Dry Needling Treatment of the Low Back: A Pilot Study
Determining the Effect of a Combination of Muscle Energy Techniques and Trigger Point Therapy on Subjective and Objective Indicators Assessing the Condition of the Musculoskeletal System in Asymptomatic Persons With Latent Trigger Point
Does Dry Needling Change Shoulder Muscle Blood Flow, Motions, and Pain Sensitivity?
The Effects of Dry Needling on Muscle Blood Flow of the Infraspinatus in Individuals with Shoulder Pain - a Randomized Controlled Trial
Effects of Myofascial Trigger Points Therapy in Migraine.
Who cites it
53 citing papers in PubMed, 141 citations in OpenAlex.
- Intramuscular electrical stimulation added to home exercise for myofascial shoulder pain: a randomized controlled trial.Scientific reports · 2026Trial
- The effects of dry needling on muscle blood flow of the infraspinatus muscle in individuals with shoulder pain - a randomized clinical trial.The Journal of manual & manipulative therapy · 2025Trial
- Electromyographic Assessment of the Efficacy of Deep Dry Needling versus the Ischemic Compression Technique in Gastrocnemius of Medium-Distance Triathletes.Sensors (Basel, Switzerland) · 2021Trial
- Alleviation of migraine symptoms by application of repetitive peripheral magnetic stimulation to myofascial trigger points of neck and shoulder muscles - A randomized trial.Scientific reports · 2020Trial
- Myofascial trigger points alter the modular control during the execution of a reaching task: a pilot study.Scientific reports · 2019Trial
- Intraosseous Lidocaine Trigger Point Injection for Vertebrogenic Pain: From Molecular Principles to Clinical Applications: A Narrative Review.International journal of molecular sciences · 2026Review
- Platelet-Rich Plasma Versus Polydeoxyribonucleotide for Myofascial Pain Syndrome and Musculoskeletal Disorders: A Narrative Review of Mechanisms, Clinical Evidence, and Translational Considerations.Bioengineering (Basel, Switzerland) · 2026Review
- Targeted cryostimulation of myofascial trigger points modulates exercise-induced physiological tremor in adolescent swimmers: a randomized counterbalanced crossover trial.BMC sports science, medicine & rehabilitation · 2026Article
- Diagnostic Utility of Surface Electromyography for Identifying Muscles Affected by Myofascial Trigger Points: A Scoping Review.Biomedicines · 2026Review
- The Role of Muscle Trigger Points in Chronic Whiplash-Associated Disorders with Neuropathic Pain Components: An Exploratory Cross-Sectional Study.Journal of clinical medicine · 2026Article
- Reframing myofascial pain syndrome: pathological disorder or adaptive protective response?Therapeutic advances in musculoskeletal disease · 2026Review
- Clinical Effectiveness of Dry Needling on Myofascial Trigger Points in Horses: A Prospective Algometric Controlled Study.Animals : an open access journal from MDPI · 2025Article
- High-Frequency Accessory and Transcapular Nerve Blocks in the Management of Fibromyalgia: A Case Report.Cureus · 2025Article
- Spectral Analysis of Bioelectrical Activity in Experimentally Provoked Referred Pain - Motor Alterations Related to the Network of Trigger Points.Journal of pain research · 2025Article
- The effect of simultaneous administration of occipital nerve block and cervical myofascial trigger point injection (MTrPI) on headache parameters in chronic migraine patients.Irish journal of medical science · 2024Article
- Biomechanically based Fu's subcutaneous needling treatment for senile knee osteoarthritis: protocol for a randomized controlled trial.Journal of orthopaedic surgery and research · 2024Article
- Intramuscular Pulsed Radiofrequency Upregulates BNDF-TrKB Expression in the Spinal Cord in Rats as an Alternative Treatment for Complicated Pain.International journal of molecular sciences · 2024Article
- Effect of dry needling, ischemic compression and cross-taping of the masseter in patients with orofacial myofascial pain: a randomized comparative study.Frontiers in oral health · 2024Article
- Article
- Myofascial Pain Syndrome in Women with Primary Dysmenorrhea: A Case-Control Study.Diagnostics (Basel, Switzerland) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Active myofascial trigger points are one of the major peripheral pain generators for regional and generalized musculoskeletal pain conditions. Myofascial trigger points are also the targets for acupuncture and/or dry needling therapies. Recent evidence in the understanding of the pathophysiology of myofascial trigger points supports The Integrated Hypothesis for the trigger point formation; however unanswered questions remain. Current evidence shows that spontaneous electrical activity at myofascial trigger point originates from the extrafusal motor endplate. The spontaneous electrical activity represents focal muscle fiber contraction and/or muscle cramp potentials depending on trigger point sensitivity. Local pain and tenderness at myofascial trigger points are largely due to nociceptor sensitization with a lesser contribution from non-nociceptor sensitization. Nociceptor and non-nociceptor sensitization at myofascial trigger points may be part of the process of muscle ischemia associated with sustained focal muscle contraction and/or muscle cramps. Referred pain is dependent on the sensitivity of myofascial trigger points. Active myofascial trigger points may play an important role in the transition from localized pain to generalized pain conditions via the enhanced central sensitization, decreased descending inhibition and dysfunctional motor control strategy.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.