ArticleActa paediatrica (Oslo, Norway : 1992)2011
Paediatric drug use with focus on off-label prescriptions in Swedish outpatient care--a nationwide study.
Article in Acta paediatrica (Oslo, Norway : 1992), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.
- [Pediatric perioperative systemic pain therapy: Austrian interdisciplinary recommendations on pediatric perioperative pain management].Schmerz (Berlin, Germany) · 2014Guideline
- Serious Adverse Drug Reactions Associated with Off-Label and Unlicensed Drug Use in Children: A 14-Year Analysis of VigiBase Reports from Serbia.Children (Basel, Switzerland) · 2026Article
- Prescription drug use in Danish children and adolescents 2005-2023.European journal of epidemiology · 2025Article
- Potential Drug-Related Problems in Pediatric Patients-Describing the Use of a Clinical Decision Support System at Pharmacies in Sweden.Pharmacy (Basel, Switzerland) · 2023Article
- From Prescription Drugs to Natural Health Products: Medication Use in Canadian Infants.Children (Basel, Switzerland) · 2022Article
- Trends in Off-Label Drug Use in Ambulatory Settings: 2006-2015.Pediatrics · 2019Article
- Article
- Two decades of off-label prescribing in children: a literature review.World journal of pediatrics : WJP · 2018Review
- Trends in Outpatient Prescription Medicine Use in New Zealand Children 2010-2015: A National Population-Based Study.Paediatric drugs · 2018Article
- Off-Label Medication use in Children, More Common than We Think: A Systematic Review of the Literature.The Journal of the Oklahoma State Medical Association · 2018Article
- A survey of medicine use in children and adolescents in Austria.European journal of pediatrics · 2018Article
- An audit on parental attitudes towards medicines used in children.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2018Article
- Use of off-label nephrology-related drugs in hospitalized pediatric patients: a retrospective study.World journal of pediatrics : WJP · 2016Article
- Unlicensed and off-label drug use in paediatrics in a mother-child tertiary care hospital.Paediatrics & child health · 2016Article
- Off-label prescribing of psychotropic drugs in a Danish child and adolescent psychiatric outpatient clinic.European child & adolescent psychiatry · 2016Article
- Off-label prescribing for allergic diseases in children.The World Allergy Organization journal · 2014Article
- Antibiotic prescription preferences in paediatric outpatient setting in Estonia and Sweden.SpringerPlus · 2013Article
- Off-label medicine use in children and adolescents: results of a population-based study in Germany.BMC public health · 2013Article
- Drug utilization pattern in an Omani pediatric population.Journal of basic and clinical pharmacy · 2013Article
- Tailored Assays for Pharmacokinetic and Pharmacodynamic Investigations of Aliskiren and Enalapril in Children: An Application in Serum, Urine, and Saliva.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAGArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo determine drug prescription and proportion of off-label dispensing in the Swedish paediatric outpatient population.
methodsAll dispensed outpatient prescriptions to children aged 0 < 18 years as well as the proportion of off-label drug use during 2007 were analysed using data from the Swedish Prescribed Drug Register.
resultsIn total, 2.19 million drug prescriptions of 898 different drug substances were dispensed to paediatric patients, and of those substances, 64% had been dispensed off-label at least once. The overall off-label rate of all prescriptions was 13.5%, among which topical drugs as well as sex hormones were the most commonly prescribed off-label drugs. More than half of all children in Sweden had received at least one prescribed drug in 2007.
conclusionsThere is a high prescribing of medicines to children in outpatient care in Sweden with a considerable amount of off-label prescriptions. Topically administered drugs, sex hormones, antidepressants, hypnotics, cardiovascular drugs and nonsteroidal anti-inflammatory drugs were commonly prescribed off-label.
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Registered trials
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