ReviewRheumatology international2011
Vascular comorbidities in familial Mediterranean fever.
Review in Rheumatology international, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 26 citations in OpenAlex.
- Vascular characteristics of pediatric patients with familial Mediterranean fever: a study of optical coherence tomography angiography findings.Japanese journal of ophthalmology · 2025Observational
- Central nervous system manifestations of monogenic autoinflammatory disorders and the neurotropic features of SARS-CoV-2: Drawing the parallels.Frontiers in pediatrics · 2022Review
- Familial Mediterranean fever and atherosclerosis in childhood and adolescence.Rheumatology international · 2020Review
- Familial Mediterranean fever: What associations to screen for?Reumatologia · 2020Review
- The Platelet-to-Lymphocyte Ratio as an Inflammatory Marker in Rheumatic Diseases.Annals of laboratory medicine · 2019Review
- Canakinumab: can it untie the Gordian knot of cardiovascular disease in patients with familial Mediterranean fever?Archives of medical sciences. Atherosclerotic diseases · 2018Article
- Cardiovascular disease in patients with autoinflammatory syndromes.Rheumatology international · 2018Review
- Vasculitis and long standing ankylosing spondylitis in a patient with familial Mediterranean fever.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2014Article
- Inflammasomes: sensors of metabolic stresses for vascular inflammation.Frontiers in bioscience (Landmark edition) · 2013Review
- Cholesterol, Inflammasomes, and Atherogenesis.Current cardiovascular risk reports · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Familial Mediterranean fever (FMF) is a common hereditary autoinflammatory disorder characterized by recurrent febrile attacks and polyserositis. The MEditerranean FeVer (MEFV) gene missense mutations altering the structure and function of pyrin protein play a significant role in the pathophysiology of the disease. Mutated pyrin is associated with the loss of delicate control of the inflammatory pathways, which results in a prolonged or augmented inflammation that predisposes these patients and carriers of the MEFV mutation to a pro-inflammatory state. This increased inflammation might lead to susceptibility to vascular comorbidities in FMF patients and even in carriers. In this review, we aim to discuss the vascular comorbidities seen in FMF patients. For this purpose, a thorough search was done in Web sites such as Pubmed, Web of Science, Scopus and Google Scholar, and the most relevant articles and case reports were evaluated. It seems that various vasculitides and the emerging problem of atherosclerosis have increasingly been recognized in these patients and, on the other hand, cardiac amyloidosis appears as a rare but devastating complication of FMF. Future studies will shed light on the unknown aspects of the emerging vascular problems in patients with FMF.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.