ArticleEuropean journal of applied physiology2011
Combined effects of chronic alcohol consumption and physical activity on bone health: study in a rat model.
Article in European journal of applied physiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Pooled it
- Comparative effects of various running exercise modalities on femoral bone quality in rats.European journal of applied physiology · 2024Article
- Effect of different running protocols on bone morphology and microarchitecture of the forelimbs in a male Wistar rat model.PloS one · 2024Article
- Effects of Different Types of Mechanical Loading on Trabecular Bone Microarchitecture in Rats.Journal of bone metabolism · 2021Article
- Cumulative Effects of Strontium Ranelate and Impact Exercise on Bone Mass in Ovariectomized Rats.International journal of molecular sciences · 2021Article
- Does Physical Exercise Always Improve Bone Quality in Rats?Life (Basel, Switzerland) · 2020Review
- The effects of concurrent training (aerobic-resistance) and milk consumption on some markers of bone mineral density in women with osteoporosis.BMC women's health · 2018Article
- Alcohol: A Simple Nutrient with Complex Actions on Bone in the Adult Skeleton.Alcoholism, clinical and experimental research · 2016Review
- Quick benefits of interval training versus continuous training on bone: a dual-energy X-ray absorptiometry comparative study.International journal of experimental pathology · 2015Article
- Alcohol and bone: review of dose effects and mechanisms.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2012Review
- Beneficial Function of Taurine on Bone Metabolism in Alcohol-Fed OVX Rat Model.Advances in experimental medicine and biologyArticle
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic alcohol consumption may be deleterious for bone tissue depending on the amount of ethanol consumed, whereas physical activity has positive effects on bone. This study was designed to analyze the effects of moderate alcohol consumption on bone in trained rats. 48 male Wistar rats were divided into four groups: control (C), alcohol (A), exercise (E) and alcohol + exercise (AE). A and AE groups drank a solution composed of water and ethanol. E and AE groups were trained for 2 months (treadmill: 40 min/day, 5 times/week). Body composition and bone mineral density (BMD) were assessed by dual X-ray absorptiometry and microarchitectural parameters using micro-computed tomography. Serum osteocalcin and CTx were determined by ELISA assays. The body weight and lean mass gain were lower in group A, while the fat mass gain was lower in exercised groups. BMD and BMC were higher with alcohol after body weight adjustment. Trabecular thickness was significantly higher in AE and A groups compared to C and E; cross-sectional area was larger in A and C groups compared to AE and E. CTx levels were higher in A compared to C and in AE and E versus C and A. Osteocalcin levels were significantly greater in AE and E groups versus C and A. In conclusion, the light to moderate alcohol consumption over a short period increased the trabecular thickness, BMC and BMD in A and AE groups. However, we observed alterations in bone remodeling and body composition with alcohol, at the end of the protocol, which did not appear when alcohol was combined to exercise.
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