Evidence map›Paper›PMID 21437578›Full record

ReviewClinical and experimental nephrology2011

Clinicopathological insights into lupus glomerulonephritis in Japanese and Asians.

Hitoshi Yokoyama, Hiroshi Okuyama, Hideki Yamaya

Abstract readReview
PubMed Publisher
In one paragraph

Review in Clinical and experimental nephrology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Long-term Outcome of Lupus Nephritis Class II in Argentine Patients: An Open Retrospective Analysis.Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases · 2016
    Article
  5. Clinical features and mortality in Chinese with lupus nephritis and neuropsychiatric lupus: A 124-patient study.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2014
    Article
  6. Lupus nephritis: maintenance therapy for lupus nephritis--do we now have a plan?Clinical journal of the American Society of Nephrology : CJASN · 2013
    Review
  7. Article
  8. Recent advances in the treatment of lupus nephritis.Clinical and experimental nephrology · 2012
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Hitoshi YokoyamaDivision of Nephrology, Kanazawa Medical University School of Medicine, Uchinada, Japan. hyokoyama-npr@umin.ac.jp.
Hiroshi OkuyamaDivision of Nephrology, Kanazawa Medical University School of Medicine, Uchinada, Japan.
Hideki YamayaDivision of Nephrology, Kanazawa Medical University School of Medicine, Uchinada, Japan.
Kanazawa Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lupus nephritis comprises a spectrum of glomerular, vascular, and tubulointerstitial lesions, which has significant racial variation in severity and manifestations. The current classification (ISN/RPS 2003) has been improved successfully for the categorization of lupus glomerulonephritis (LGN). On the basis of this classification, 480 Japanese cases revealed the following distribution: class I 3%, class II 16%, class III 13%, class IV-S 11%, class IV-G 41%, class V 16%, and class VI 1%. Class IV-G with chronicity tended to have the worst renal outcome. Nephrotic syndrome was a more frequent complication in class IV-S (50%), class IV-G (72%), and class V (56%), with poor renal and actuarial outcomes. With regard to therapy, treatment options including glucocorticoids alone or combined with antimetabolites (azathioprine, mizoribine, mycophenolate mofetil), calcineurin inhibitors (cyclosporine A, tacrolimus), or alkylating agents (intravenous cyclophosphamide injection) improved the outcome of LGN; however, there is no high-grade clinical evidence from Japan. Further studies are needed to resolve the clinicopathological problems of LGN, especially IV-S, IV-G, and pure membranous lupus nephritis in Japanese patients.

Indexed as

AdultAsian PeopleGlomerulonephritis, MembranoproliferativeHumansJapanLupus Erythematosus, SystemicLupus NephritisMiddle AgedTreatment Outcome

Identifiers

PMID21437578
OpenAlexW1985311282

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.