Evidence map›Paper›PMID 21437048›Full record

ArticleJournal of asthma and allergy2010

The effect of Helicobacter pylori on asthma and allergy.

Amedeo Amedei, Gaia Codolo, Gianfranco Del Prete, Marina de Bernard, Mario M D'Elios

Open access · goldAbstract read
In one paragraph

Article in Journal of asthma and allergy, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Microorganisms · 2023
    Review
  5. The Protective Effects of Helicobacter pylori Infection on Allergic Asthma.International archives of allergy and immunology · 2021
    Review
  6. Curcumin Oxidation Is Required for Inhibition ofFrontiers in cellular and infection microbiology · 2021
    Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. The Eurasian journal of medicine · 2019
    Review
  12. The World Allergy Organization journal · 2019
    Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. The microbiome, HLA, and the pathogenesis of uveitis.Japanese journal of ophthalmology · 2016
    Review
  19. Diseases (Basel, Switzerland) · 2015
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Amedeo AmedeiPoliclinico AOU Careggi, Department Internal Medicine, University of Florence, Italy;
Gaia Codolo
Gianfranco Del Prete
Marina de Bernard
Mario M D'Elios
Azienda Ospedaliero-Universitaria Careggi · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Current evidence indicates an inverse association between Helicobacter pylori and asthma and allergy. H. pylori is a Gram-negative bacterium which represents the major cause of peptic ulcer and gastric cancer, and preferentially elicits a T helper (Th)-1 response. Many H. pylori factors, such as the neutrophil-activating factor of H. pylori (HP-NAP), are able to drive Th-1 polarization and to display a powerful inhibition of allergic Th-2 response. This article proposes an overview of the actual knowledge about the effects of H. pylori on asthma and allergy. Special attention has been drawn to HP-NAP as a potential novel strategy for the prevention and treatment of asthma and atopy.

Indexed as

asthmaHelicobacter pylori neutrophil-activating factorproteinTh-1/Th-2Treg

Identifiers

PMID21437048
PMCPMC3047919
OpenAlexW1986228083

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.