ArticleGastroenterology & hepatology2010
The Role of MicroRNA in Inflammatory Bowel Disease.
Article in Gastroenterology & hepatology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
83 citing papers in PubMed.
- Analysis of Colon Transcriptomes in a Porcine Model of Dextran Sodium Sulfate (DSS)-Induced Ulcerative Colitis.Biology · 2026Article
- Advances in biosensors for diagnosis and monitoring of inflammatory bowel disease: A review.Bioengineering & translational medicine · 2025Review
- Article
- The Role of microRNAs in Inflammatory Bowel Disease.International journal of molecular sciences · 2025Review
- Exploring the effect of hsa-miR-19b-3p on IL-1R1 expression and serum levels in alopecia areata.Archives of dermatological research · 2025Article
- MicroRNA signatures in the pathogenesis and therapy of inflammatory bowel disease.Clinical and experimental medicine · 2024Review
- MicroRNAs in inflammatory bowel disease: What do we know and what can we expect?World journal of gastroenterology · 2024Article
- Duodenal Crohn's disease: Case report and systematic review.World journal of methodology · 2024Article
- Mathematical Models Including microRNA Levels of Mesenteric Adipose Tissue May Predict Postoperative Relapse in Crohn's Disease Patients.Gastro hep advances · 2024Article
- Exosome-shuttled miR-150-5p from LPS-preconditioned mesenchymal stem cells down-regulate PI3K/Akt/mTOR pathway via Irs1 to enhance M2 macrophage polarization and confer protection against sepsis.Frontiers in immunology · 2024Article
- Horizon scanning: new and future therapies in the management of inflammatory bowel disease.eGastroenterology · 2023Review
- A Systems Biology Approach to Identify Novel Biomarkers in Progression from Crohn's Disease to Colorectal Cancer.Asian Pacific journal of cancer prevention : APJCP · 2023Article
- Epigenetics of Inflammatory Bowel Diseases.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2023Article
- Intestinal Microbiota and miRNA in IBD: A Narrative Review about Discoveries and Perspectives for the Future.International journal of molecular sciences · 2023Review
- Review
- Hsa-miR-422a Originated from Short Interspersed Nuclear Element IncreasesMolecules and cells · 2022Article
- Improved prediction of radiation pneumonitis by combining biological and radiobiological parameters using a data-driven Bayesian network analysis.Translational oncology · 2022Article
- The Increase of miR-195-5p Reduces Intestinal Permeability in Ulcerative Colitis, Modulating Tight Junctions' Expression.International journal of molecular sciences · 2022Article
- miR-195-5p Regulates Tight Junctions Expression via Claudin-2 Downregulation in Ulcerative Colitis.Biomedicines · 2022Article
- The spring-like effect of microRNA-31 in balancing inflammatory and regenerative responses in colitis.Frontiers in microbiology · 2022Article
23 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Inflammatory bowel disease (IBD) is the consequence of an abnormal immune response to environmental factors in genetically susceptible hosts. microRNAs (miRNAs) are small, 22-nucleotide, noncoding, single-stranded RNA molecules involved in the post-tran-scriptional regulation of 30% of protein-coding genes. Differential expression of miRNAs is described in multiple autoimmune-related conditions such as psoriasis, rheumatoid arthritis, lupus, and asthma. Recently, unique miRNA expression profiles have been described in epithelial cells of patients with active ulcerative colitis, Crohn's ileitis, and Crohn's colitis, as well as in the peripheral blood of patients with active ulcerative colitis and Crohn's disease. miRNA expression profiles also change in the progression from normal colonic tissue to dysplastic tissue, with unaffected tissue from IBD patients and inflamed tissue from IBD patients showing intermediate profiles. Understanding the role of miRNAs in IBD may lead to future insights into disease pathogenesis, diagnosis, and treatment.
Indexed as
Identifiers
21437020PMC3033542What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.