ArticleThe Plant journal : for cell and molecular biology2011
AtPPR2, an Arabidopsis pentatricopeptide repeat protein, binds to plastid 23S rRNA and plays an important role in the first mitotic division during gametogenesis and in cell proliferation during embryogenesis.
Article in The Plant journal : for cell and molecular biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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25 citing papers in PubMed, 44 citations in OpenAlex.
- Defective Processing of Cytoplasmic and Chloroplast Ribosomal RNA in the Absence of Arabidopsis DXO1.Plant, cell & environment · 2025Article
- A PPR Protein RFCD1 Affects Chloroplast Gene Expression and Chloroplast Development inPlants (Basel, Switzerland) · 2025Article
- Loss of both wobbleUFrontiers in plant science · 2025Article
- Functions of PPR Proteins in Plant Growth and Development.International journal of molecular sciences · 2021Review
- Temporal Control of Seed Development in Dicots: Molecular Bases, Ecological Impact and Possible Evolutionary Ramifications.International journal of molecular sciences · 2021Review
- The Arabidopsis NOT4A E3 ligase promotes PGR3 expression and regulates chloroplast translation.Nature communications · 2021Article
- Maize kernel development.Molecular breeding : new strategies in plant improvement · 2021Review
- A new method for functional analysis of plastid EMBRYO-DEFECTIVE PPR genes by efficiently constructing cosuppression lines in Arabidopsis.Plant methods · 2020Article
- Roles of Organellar RNA-Binding Proteins in Plant Growth, Development, and Abiotic Stress Responses.International journal of molecular sciences · 2020Review
- PDM4, a Pentatricopeptide Repeat Protein, Affects Chloroplast Gene Expression and Chloroplast Development inFrontiers in plant science · 2020Article
- Integrated microRNA and transcriptome profiling reveals a miRNA-mediated regulatory network of embryo abortion under calcium deficiency in peanut (Arachis hypogaea L.).BMC genomics · 2019Article
- Peg Biology: Deciphering the Molecular Regulations Involved During Peanut Peg Development.Frontiers in plant science · 2019Review
- Detecting the QTL-allele system conferring flowering date in a nested association mapping population of soybean using a novel procedure.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2017Article
- Small RNA profiling and degradome analysis reveal regulation of microRNA in peanut embryogenesis and early pod development.BMC genomics · 2017Article
- Over-expression of miR158 causes pollen abortion in Brassica campestris ssp. chinensis.Plant molecular biology · 2017Article
- Transcriptome Analysis of Flower Sex Differentiation in Jatropha curcas L. Using RNA Sequencing.PloS one · 2016Article
- The conserved endoribonuclease YbeY is required for chloroplast ribosomal RNA processing in Arabidopsis.Plant physiology · 2015Article
- Phenotype to genotype using forward-genetic Mu-seq for identification and functional classification of maize mutants.Frontiers in plant science · 2014Article
- Empty pericarp5 encodes a pentatricopeptide repeat protein that is required for mitochondrial RNA editing and seed development in maize.The Plant cell · 2013Article
- Arabidopsis thaliana Oxa proteins locate to mitochondria and fulfill essential roles during embryo development.Planta · 2013Article
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Authors and funding
6 authors at 3 institutions in 3 countries.
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Abstract
Pentatricopeptide repeat (PPR) proteins are mainly involved in regulating post-transcriptional processes in mitochondria and plastids, including chloroplasts. Mutations in the Arabidopsis PPR2 gene have previously been found to cause defects in seed development and reduced transmission through male and female gametophytes. However, the exact function of AtPPR2 has not been defined. We found that a loss-of-function mutation of AtPPR2 leads to arrest of the first mitotic division during both male and female gametogenesis. In addition, the Atppr2 mutation causes delayed embryogenesis, leading to embryonic lethality. Mutation in emb2750, which appears to be a weak mutant allele of the AtPPR2 locus, also results in defective seeds. However, a majority of emb2750 seeds were able to germinate, but their cotyledons were albino and often deformed, and growth of the emb2750 seedlings were arrested after germination. AtPPR2 is mainly expressed in plant parts that undergo cell division, and AtPPR2 protein was localized to chloroplasts. RNA immunoprecipitation and protein gel mobility shift assays showed that AtPPR2 binds to plastid 23S rRNA. Our study adds to a growing body of evidence that plastids and/or chloroplasts play a key role in cell division. AtPPR2 may modulate the translational process to fine-tune plastid function, thereby regulating cell division.
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