Evidence map›Paper›PMID 2143503›Full record

ArticleJournal of anatomy1990

Appearance of laminin, heparan sulphate proteoglycan and collagen type IV during initial stages of vascularisation of the neuroepithelium of the mouse embryo.

R Herken, W Götz, M Thies

Abstract read
In one paragraph

Article in Journal of anatomy, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. The neurovascular unit in the setting of stroke.Journal of internal medicine · 2010
    Review
  3. Review
  4. Relationship of neurovascular elements to neuron injury during ischemia.Cerebrovascular diseases (Basel, Switzerland) · 2009
    Review
  5. Virchow's triad: the vascular basis of cerebral injury.Reviews in neurological diseases · 2008
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

R HerkenZentrum Anatomie, Abteilung Histologie, Göttingen, FRG.
W Götz
M Thies
Universitätsmedizin Göttingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The appearance of the basement membrane components laminin, heparan sulphate proteoglycan and Type IV collagen was investigated by indirect immunofluorescence during the onset of vascularisation of the neuroepithelium of mouse embryos (Days 10, 11 and 12 of development). All three basement membrane components could initially be seen in the embryonic CNS anlage along with the appearance of capillaries in the neuroepithelial cell layer. From this direct correlation between vascularisation and appearance of basement membrane components in the embryonic anlage one can assume that the basement membrane components laminin, heparan sulphate proteoglycan and collagen Type IV are involved in the initial vascularisation of the CNS anlage of 10 to 12 day old mouse embryos.

Indexed as

AnimalsCapillariesCell MembraneCentral Nervous SystemCollagenEpitheliumExtracellular MatrixFemaleGlycosaminoglycansHeparan SulfateImmunohistochemistryLamininMicePregnancyCollagenGlycosaminoglycansHeparan SulfateLaminin

Identifiers

PMID2143503
PMCPMC1256966
OpenAlexW1577314072

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.