Evidence map›Paper›PMID 21432329›Full record

ArticleEnvironmental health and preventive medicine2004

Effect of black tea aqueous non-dialysate onHelicobacter pylori infection in Mongolian gerbils.

Fumiyo Takabayashi, Yoshiyuki Nakamura, Noboru Harada

Open access · bronzeAbstract read
In one paragraph

Article in Environmental health and preventive medicine, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Fumiyo TakabayashiJunior College, University of Shizuoka, 2-2-1 Oshika, 422-8021, Shizuoka-shi, Shizuoka Prefecture, Japan, tkbys@bambisi-shizuoka-ken.ac.jp.
Yoshiyuki Nakamura
Noboru Harada
Shizuoka University · JPSugiyama Jogakuen University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesRecently, the appearance ofHelicobacter pylori (H. pylori) resistant to antibiotics has been reported. The development of an antibiotic therapy which would not induce resistant strains ofH. pylori is anticipated. In the present study, the antibiotic effect of black tea aqueous non-dialysate (BTND), the fraction different from tea catechins, onH. pylori was investigated using Mongolian gerbils infected withH. pylori.

methodsBTND was extracted from black tea leaves. A 0.1 w/v% solution of BTND or green tea catechins (GTC) was provided as drinking water to male NGS/Sea Mongolian gerbils infected withH. pylori (ATCC43504) for two weeks. Their stomachs were then excised, the mucosal surfaces were macroscopically observed, and colony forming units (CFU) ofH. pylori were counted. The data were compared between the BTND and GTC groups.

resultsThe CFU ofH. pylori were significantly decreased by intake of BTND. The body weight of the animals tended to be larger in the group supplied with BTND than in that supplied with GTC. Gastric mucosal injury tended to be smaller in the animals supplied with BTND than in those with GTC.

conclusionsThese results suggest that BTND may have an inhibitory effect onH. pylori infection.

Indexed as

gastric mucosal erosiongreen tea catechinsHelicobacter pyloriMongolian gerbiltea aqueous non-dialysate

Identifiers

PMID21432329
PMCPMC2723575
OpenAlexW1978720625

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.