Evidence map›Paper›PMID 21432323›Full record

ArticleEnvironmental health and preventive medicine2004

Methodological issues for a large-scale intervention trial of lifestyle modification: Interim assessment of the high-risk and population strategy for occupational health promotion (HIPOP-OHP) study.

Tomonori Okamura, Taichiro Tanaka, Toru Takebayashi, Hideaki Nakagawa, Hiroshi Yamato, Katsushi Yoshita, Takashi Kadowaki, Akira Okayama, Hirotsugu Ueshima, HIPOP-OHP research group

Abstract read
In one paragraph

Article in Environmental health and preventive medicine, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Workplace interventions for smoking cessation.The Cochrane database of systematic reviews · 2014
    Pooled it
  2. Article
  3. Association of blood pressure with estimates of 24-h urinary sodium and potassium excretion from repeated single-spot urine samples.Hypertension research : official journal of the Japanese Society of Hypertension · 2019
    Article
  4. Salt reduction in a population for the prevention of hypertension.Environmental health and preventive medicine · 2004
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tomonori OkamuraDepartment of Health Science, Shiga University of Medical Science Seta, Tsukinewa-cho, 520-2192, Otsu, Japan, tokamura@belle.saiga-med.ac.jp.
Taichiro Tanaka
Toru Takebayashi
Hideaki Nakagawa
Hiroshi Yamato
Katsushi Yoshita
Takashi Kadowaki
Akira Okayama
Hirotsugu Ueshima
HIPOP-OHP research group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo clarify the methodological issues for the High-risk and population Strategy for Occupational Health Promotion Study (HIPOP-OHP study), which is a 4-year non-randomized control trial, an interim assessment of male participants was performed 3 years after the baseline survey.

methodsWe had approximately 2,500 and 4,000 participants in the intervention and control groups, respectively. The population measures and prevalence of risk factors at each year, and between the baseline and 4th examinations were compared between the two groups. The personal trends of returning participants who were in the study at the 1(st) and 4(th) examinations were also evaluated.

resultsDuring the 3 years, an increase in serum HDL cholesterol (2.7 mg/dl), and a reduction in the prevalence of hypertriglycemia detected with fasting blood samples (3.6%) and current smokers (5.4%) were observed in the intervention group. The mean HDL cholesterol level was significantly higher in the intervention group than in the control group at the 4th examination, reversed from the baseline survey. The serum non-HDL cholesterol level was significantly increased only in the control group. There was also a significant increase in the prevalence of hypertriglycemia nad high plasma glucose detected with fasting blood samples in the control group. The return participation rate after 3 years was 72.2% for the intervention group and 74.9% for the control group. The above-mentioned changes for risk factors were mainly due to returning participants at each examination.

conclusionThese interventional methods may be effective in improving overall cardiovascular risk factors in the population. However, the low return participation rate will dilute the effect of the intervention.

Indexed as

cardiovascular risk factorinterim assessmentinterventionpopulation strategyreturn participation

Identifiers

PMID21432323
PMCPMC2723569

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.