Evidence map›Paper›PMID 21431789›Full record

ArticleEnvironmental health and preventive medicine2011

Installation of mechanical ventilation in a horse stable: effects on air quality and human and equine airways.

Robert Wålinder, Miia Riihimäki, Susanne Bohlin, Carl Hogstedt, Tobias Nordquist, Amanda Raine, John Pringle, Lena Elfman

Abstract readEvaluation Study
In one paragraph

Article in Environmental health and preventive medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Fungal aerosol and particulate matter in horse stables in Poland.Applied microbiology and biotechnology · 2024
    Article
  3. Article
  4. Environmental Management of Equine Asthma.Animals : an open access journal from MDPI · 2024
    Review
  5. Review
  6. Frontiers in immunology · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Increased Weekly Mean PMFrontiers in veterinary science · 2020
    Article
  12. Comparative Review of Asthma in Farmers and Horses.Current allergy and asthma reports · 2019
    Review
  13. Article
  14. Article
  15. Observational
  16. Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Robert WålinderDepartment of Medical Sciences, Occupational and Environmental Medicine, Uppsala University Hospital, University of Uppsala, 751 85, Uppsala, Sweden. robert.walinder@medsci.uu.se
Miia Riihimäki
Susanne Bohlin
Carl Hogstedt
Tobias Nordquist
Amanda Raine
John Pringle
Lena Elfman

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo examine the effects of installing a mechanical ventilation system at a riding-school stable on indoor air quality and human and horse airways.

methodsThe intervention was the installation of mechanical ventilation in a riding-school stable. Carbon dioxide (CO2), ammonia, particles, horse allergen, microorganisms and endotoxins were measured in the stable. The stable-workers and riding-students completed a questionnaire and underwent the following tests: analysis of nasal lavage for inflammation biomarkers; levels of exhaled nitrogen oxide (NO); measurements of daily peak-expiratory flow (PEF). The horses were examined clinically by airway endoscopy and bronchoalveolar lavage (BAL) and were analysed for cytology and biomarkers.

resultsLevels of CO2 were nearly halved and airborne horse allergen levels were markedly reduced (5-0.8 kU/m3) after the intervention. A decreased level of ultrafine particles was observed (8000-5400 particles/cm3) after the intervention, while total and respirable dust levels were mainly unchanged (200 and 130 μg/m3). Levels of microorganisms in surface samples decreased following the intervention, whereas airborne microorganisms and endotoxin increased. There was no significant change in human symptoms, PEF-variability, exhaled NO or inflammatory biomarkers in the nasal lavage. In horses, the mean score of lower airway mucus was significantly reduced together with the mean level of expression of interleukin-6 mRNA in BAL cells after the intervention.

conclusionsThe installation of a mechanical ventilation system resulted in an increased air exchange rate, as demonstrated by reduced levels of CO2, ammonia, ultrafine particles and horse allergen. There was no significant clinical effect on human airways, but there was a tendency for reduced inflammation markers. The results on the horses may indicate less impact on their airways after the intervention.

Indexed as

HorsesHousing, AnimalAdolescentAdultAir PollutantsAir Pollution, IndoorAnimalsBronchoalveolar LavageBronchoscopyFemaleHumansMaleMiddle AgedNasal LavageNitric OxideOccupational ExposureAir PollutantsNitric Oxide

Identifiers

PMID21431789
PMCPMC3117214

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.