Evidence map›Paper›PMID 21431757›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2011

Identifying and searching for conserved RNA localisation signals.

Russell S Hamilton, Ilan Davis

Abstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Evolution of the unspliced transcriptome.BMC evolutionary biology · 2015
    Article
  8. Article
  9. Article
  10. Article
  11. Identification of a cis-acting element that localizes mRNA to synapses.Proceedings of the National Academy of Sciences of the United States of America · 2012
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Russell S HamiltonDepartment of Biochemistry, University of Oxford, Oxford, UK.
Ilan Davis

Funding

Wellcome Trust 081858
6 · The paper itself

Abstract

RNA localisation is an important mode of delivering proteins to their site of function. Cis-acting signals within the RNAs, which can be thought of as zip-codes, determine the site of localisation. There are few examples of fully characterised RNA signals, but the signals are thought to be defined through a combination of primary, secondary, and tertiary structures. In this chapter, we describe a selection of computational methods for predicting RNA secondary structure, identifying localisation signals, and searching for similar localisation signals on a genome-wide scale. The chapter is aimed at the biologist rather than presenting the details of each of the individual methods.

Indexed as

Base SequenceComputational BiologyConserved SequenceIntracellular SpaceMolecular Sequence DataNucleic Acid ConformationRepetitive Sequences, Nucleic AcidRNARNA-Binding ProteinsRNA, MessengerRNA TransportSequence AlignmentSequence Homology, Nucleic AcidRNARNA-Binding ProteinsRNA, Messenger

Identifiers

PMID21431757
PMCPMC3082378

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.