Evidence map›Paper›PMID 21431335›Full record

ArticleJournal of structural and functional genomics2011

First experiences with semi-autonomous robotic harvesting of protein crystals.

Robert Viola, Jace Walsh, Alex Melka, Wesley Womack, Sean Murphy, Alan Riboldi-Tunnicliffe, Bernhard Rupp

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of structural and functional genomics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Automated harvesting and processing of protein crystals through laser photoablation.Acta crystallographica. Section D, Structural biology · 2016
    Article
  4. Article
  5. An evaluation of adhesive sample holders for advanced crystallographic experiments.Acta crystallographica. Section D, Biological crystallography · 2014
    Article
  6. Approaches to automated protein crystal harvesting.Acta crystallographica. Section F, Structural biology communications · 2014
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Robert ViolaSquare One Systems Design, Jackson, WY 83002, USA.
Jace Walsh
Alex Melka
Wesley Womack
Sean Murphy
Alan Riboldi-Tunnicliffe
Bernhard Rupp

Funding

A Universal Micromanipulation Robot for CrystallographyR42GM073278 · NIGMS · SQUARE ONE SYSTEMS DESIGN · PI VIOLA, ROBERT · 2008 to 2009
$1.3M
NIGMS NIH HHS R42 GM073278-02A1
6 · The paper itself

Abstract

The demonstration unit of the Universal Micromanipulation Robot (UMR) capable of semi-autonomous protein crystal harvesting has been tested and evaluated by independent users. We report the status and capabilities of the present unit scheduled for deployment in a high-throughput protein crystallization center. We discuss operational aspects as well as novel features such as micro-crystal handling and drip-cryoprotection, and we extrapolate towards the design of a fully autonomous, integrated system capable of reliable crystal harvesting. The positive to enthusiastic feedback from the participants in an evaluation workshop indicates that genuine demand exists and the effort and resources to develop autonomous protein crystal harvesting robotics are justified.

Indexed as

RoboticsAutomation, LaboratoryCrystallographyErgonomicsHumansMiniaturizationProteinsProteins

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.