Trial reportPsychopharmacology2011
Dexamphetamine effects on separate constructs in the rubber hand illusion test.
Trial report in Psychopharmacology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 38 citations in OpenAlex.
- The effect of a synthetic cannabinoid agonist (nabilone) on unimodal tactile illusion correlates with a psychometric scores in healthy volunteers.Scientific reports · 2025Trial
- The effects of caffeine and d-amphetamine on spatial span task in healthy participants.PloS one · 2023Trial
- Dexamphetamine widens temporal and spatial binding windows in healthy participants.Journal of psychiatry & neuroscience : JPNTrial
- Arousal, interindividual differences and temporal binding a psychophysiological study.Psychological research · 2024Article
- Article
- Body transfer illusions in the schizophrenia spectrum: a systematic review.Schizophrenia (Heidelberg, Germany) · 2022Review
- Differential contributions of serotonergic and dopaminergic functional connectivity to the phenomenology of LSD.Psychopharmacology · 2022Article
- Deficits in Sense of Body Ownership, Sensory Processing, and Temporal Perception in Schizophrenia Patients With/Without Auditory Verbal Hallucinations.Frontiers in neuroscience · 2022Article
- Autism and psychosis as diametrical disorders of embodiment.Evolution, medicine, and public health · 2019Article
- "Fake it till You Make it"! Contaminating Rubber Hands ("Multisensory Stimulation Therapy") to Treat Obsessive-Compulsive Disorder.Frontiers in human neuroscience · 2019Article
- COMT genotype is associated with plasticity in sense of body ownership: a pilot study.Psychological research · 2018Article
- Anomalous bodily experiences and perceived social isolation in schizophrenia: An extension of the Social Deafferentation Hypothesis.Schizophrenia research · 2016Article
- Application of the rubber hand illusion paradigm: comparison between upper and lower limbs.Psychological research · 2016Article
- The effects of dexamphetamine on the resting-state electroencephalogram and functional connectivity.Human brain mapping · 2016Article
- Social anxiety disorder and the psychobiology of self-consciousness.Frontiers in human neuroscience · 2015Review
- When Passive Feels Active--Delusion-Proneness Alters Self-Recognition in the Moving Rubber Hand Illusion.PloS one · 2015Article
- Deficits in agency in schizophrenia, and additional deficits in body image, body schema, and internal timing, in passivity symptoms.Frontiers in psychiatry · 2014Article
- Could dopamine agonists aid in drug development for anorexia nervosa?Frontiers in nutrition · 2014Review
- The computational anatomy of psychosis.Frontiers in psychiatry · 2013Article
- Dexamphetamine selectively increases 40 Hz auditory steady state response power to target and nontarget stimuli in healthy humans.Journal of psychiatry & neuroscience : JPN · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
rationaleCorporeal awareness is an integral component of self-consciousness and is distorted in several neurological and psychiatric disorders. Research regarding the neural underpinnings of corporeal awareness has made much progress recently using the rubber hand illusion (RHI) procedure. However, more studies are needed to investigate the possibility of several dissociable constructs related to the RHI specifically, and corporeal awareness generally.
objectivesConsidering dopamine's involvement in many perceptual-motor learning processes, as well as its apparent relationship with disorders such as schizophrenia that are linked to body ownership disturbances, we gave 0.45 mg/kg dexamphetamine (a dopamine transporter reverser) to 20 healthy participants to examine the effects of increased dopamine transmission on the RHI.
methodsThe effect of dexamphetamine on separate quantitative constructs underlying RHI were examined including embodiment of rubber hand, loss of ownership of real hand, perception of movement, affect, deafference, and proprioceptive drift. The experiment was a double-blind, placebo-controlled, cross-over design.
resultsDexamphetamine increased participants' ratings of embodiment (particularly "ownership") of the rubber hand and was associated with the experience of loss of ownership of the person's real hand. There were significant increases from asynchronous to synchronous stroking for the measures of movement and proprioceptive drift after placebo but not dexamphetamine. There were no changes in the measures of other constructs.
conclusionsThese results show a novel pharmacological manipulation of separate constructs of the RHI. This finding may aid in our understanding of disorders that have overlapping disturbances in both dopamine activity and body representations, particularly schizophrenia.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.