ArticleDose-response : a publication of International Hormesis Society2010
Epidemiological Evidence for Possible Radiation Hormesis from Radon Exposure: A Case-Control Study Conducted in Worcester, MA.
Article in Dose-response : a publication of International Hormesis Society, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Human Health Impacts of Residential Radon Exposure: Updated Systematic Review and Meta-Analysis of Case-Control Studies.International journal of environmental research and public health · 2022Pooled it
- The impact of low-dose gamma radiation on immune modulation in a mouse model of spontaneous mammary gland tumorigenesis.Frontiers in immunology · 2025Article
- Evaluating thyroid cancer risks for nuclear workers related to the Fukushima Daiichi Nuclear Power Plant accident based on LNT theory is problematic.Journal of radiation research · 2024Article
- The Hormesis Concept: Strengths and Shortcomings.Biomolecules · 2023Review
- Correlative links between natural radiation and life expectancy in the US population.Biogerontology · 2022Article
- Effects of Chronic Low-Dose Internal Radiation on Immune-Stimulatory Responses in Mice.International journal of molecular sciences · 2021Article
- Cancer immunotherapy: how low-level ionizing radiation can play a key role.Cancer immunology, immunotherapy : CII · 2017Review
- Lung cancer hormesis in high impact states where nuclear testing occurred.Clinical lung cancer · 2015Article
- Commentary: ethical issues of current health-protection policies on low-dose ionizing radiation.Dose-response : a publication of International Hormesis Society · 2014Article
- Linear No-Threshold Model VS. Radiation Hormesis.Dose-response : a publication of International Hormesis Society · 2013Article
- First generation stochastic gene episilencing (step1) model and applications to in vitro carcinogen exposure.Dose-response : a publication of International Hormesis Society · 2013Article
- NRF2 and the Phase II Response in Acute Stress Resistance Induced by Dietary Restriction.Journal of clinical & experimental pathology · 2012Article
- Residential radon appears to prevent lung cancer.Dose-response : a publication of International Hormesis Society · 2011Article
- Influence of Individual Radiosensitivity on the Hormesis Phenomenon: Toward a Mechanistic Explanation Based on the Nucleoshuttling of ATM Protein.Dose-response : a publication of International Hormesis SocietyReview
- Epidemiologic Studies Cannot Reveal the True Shape of the Dose-Response Relationship for Radon-Induced Lung Cancer.Dose-response : a publication of International Hormesis SocietyArticle
- Health Impacts of Low-Dose Ionizing Radiation: Current Scientific Debates and Regulatory Issues.Dose-response : a publication of International Hormesis SocietyReview
- A Critique of Recent Epidemiologic Studies of Cancer Mortality Among Nuclear Workers.Dose-response : a publication of International Hormesis SocietyArticle
- Treatment of Cancer and Inflammation With Low-Dose Ionizing Radiation: Three Case Reports.Dose-response : a publication of International Hormesis SocietyArticle
- Radiophobia Harm, Its Main Cause, and a Proposed Solution.Dose-response : a publication of International Hormesis SocietyArticle
- A Breakthrough on Modeling Cancer Prevention and Elimination by Low Radiation Doses.Dose-response : a publication of International Hormesis SocietyArticle
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Abstract
Data from a case-control study of lung cancer and residential radon exposure conducted in Worcester County, Massachusetts, are presented. Lung cancer risk was estimated using conditional logistic regression models that controlled for demographic, smoking, and occupational exposure covariates. Preliminary exploratory analyses using lowess smoothing revealed a non-linear association between exposure and the log odds of lung cancer. Radon exposure was considered by using linear spline terms in order to model this nonlinearity. The best fit of this linear spline model to these data predicted a shift from a positive to a negative slope in the log-odds of lung cancer at a radon concentration of 70 Bq m(-3). A statistically significant decrease in cancer risk with increased exposure was found for values ≤ 157 Bq m(-3) normalized to the reference exposure of 4.4 Bq m(-3), the lowest radon concentration measured(adjusted odds ratio (AOR) [95% CI] = 0.42 [0.180, 1.00], p = 0.049). This result is consistent with those reported elsewhere that considered radon exposure with cubic spline terms (Thompson, RE et al. 2008). Furthermore, this model predicts an AOR that is numerically less than 1.0 for radon exposures up to 545 Bq m(-3) versus the above baseline, reference exposure.
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