ArticleDose-response : a publication of International Hormesis Society2010
Cancer mortality in six lowest versus six highest elevation jurisdictions in the u.s.
Article in Dose-response : a publication of International Hormesis Society, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Misleading Model: Why the 5% Cancer Risk from Computed Tomography Scans Is Overstated.American journal of respiratory and critical care medicine · 2025Article
- Effects of pressure on the survival and viability of cancer cells in vitro: An analytical study.PloS one · 2025Article
- Background radiation impacts human longevity and cancer mortality: reconsidering the linear no-threshold paradigm.Biogerontology · 2021Article
- Cancer risk associated with living at high altitude in Ecuadorian population from 2005 to 2014.Clujul medical (1957) · 2018Article
- Article
- Cancer mortality for a single race in low versus high elevation counties in the u.s.Dose-response : a publication of International Hormesis Society · 2011Article
- Are Restrictive Medical Radiation Imaging Campaigns Misguided? It Seems So: A Case Example of the American Chiropractic Association's Adoption of "Choosing Wisely".Dose-response : a publication of International Hormesis SocietyArticle
- X-Ray Hesitancy: Patients' Radiophobic Concerns Over Medical X-rays.Dose-response : a publication of International Hormesis SocietyArticle
- Health Impacts of Low-Dose Ionizing Radiation: Current Scientific Debates and Regulatory Issues.Dose-response : a publication of International Hormesis SocietyReview
- Reduced Lung Cancer Mortality With Lower Atmospheric Pressure.Dose-response : a publication of International Hormesis SocietyArticle
- Association Between Air Temperature and Cancer Death Rates in Florida: An Ecological Study.Dose-response : a publication of International Hormesis SocietyArticle
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Authors and funding
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Abstract
Low levels of background radiation exist around us continuously. These levels increase with increasing land elevation, allowing a comparison of low elevations to high elevations in regard to an outcome such as cancer death rates. The present study compares archived cancer mortality rates in six low versus six high elevation jurisdictions. The study also compares mortality rates for all causes, heart disease, and diabetes in low versus high elevation jurisdictions in an effort to see if other mortality outcomes are different in low versus high elevations. Statistically significant decreases in mortality, with very large effect sizes, were observed in high land elevation for three of the four outcomes, including cancer. One possible explanation for the decreased mortality in high elevation jurisdictions is radiation hormesis. Another possible explanation, at least in the case of heart disease mortality, is the physiologic responses that accompany higher elevations regarding decreased oxygen levels. Since this is an ecological study, no causal inferences can be made, particularly when viewpoints on possible effects of low level radiation are diametrically opposed. Further research is indicated.
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