ArticleJournal of pharmacy & bioallied sciences2011
Biomembrane models and drug-biomembrane interaction studies: Involvement in drug design and development.
Article in Journal of pharmacy & bioallied sciences, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed.
- Bitopic AJournal of medicinal chemistry · 2025Article
- Secondary metabolites in topical infectious diseases and nanomedicine applications.Nanomedicine (London, England) · 2024Review
- Interaction ofJournal of functional biomaterials · 2023Article
- A Thermodynamic Study on the Interaction between RH-23 Peptide and DMPC-Based Biomembrane Models.Membranes · 2022Article
- States of Aggregation and Phase Transformation Behavior of Metallosurfactant Complexes by Hexacyanoferrate(II): Thermodynamic and Kinetic Investigation of ETR in Ionic Liquids and Liposome Vesicles.Biomimetics (Basel, Switzerland) · 2022Article
- Interaction of Lipophilic Cytarabine Derivatives with Biomembrane Model at the Air/Water Interface.Membranes · 2022Article
- Methods of Liposomes Preparation: Formation and Control Factors of Versatile Nanocarriers for Biomedical and Nanomedicine Application.Pharmaceutics · 2022Review
- A Biophysical Insight of Camptothecin Biodistribution: Towards a Molecular Understanding of Its Pharmacokinetic Issues.Pharmaceutics · 2021Article
- Effect of Selected Anionic and Cationic Drugs Affecting the Central Nervous System on Electrical Properties of Phosphatidylcholine Liposomes: Experiment and Theory.International journal of molecular sciences · 2021Article
- Curcumin Loaded Polymeric vs. Lipid Nanoparticles: Antioxidant Effect on Normal and Hypoxic Olfactory Ensheathing Cells.Nanomaterials (Basel, Switzerland) · 2021Article
- Lipid Nanosystems and Serum Protein as Biomimetic Interfaces: Predicting the Biodistribution of a Caffeic Acid-Based Antioxidant.Nanotechnology, science and applications · 2021Article
- Structural Characterization of Biomaterials by Means of Small Angle X-rays and Neutron Scattering (SAXS and SANS), and Light Scattering Experiments.Molecules (Basel, Switzerland) · 2020Review
- Teicoplanin-Modified HPLC Column as a Source of Experimental Parameters for Prediction of the Anticonvulsant Activity of 1,2,4-Triazole-3-Thiones by the Regression Models.Materials (Basel, Switzerland) · 2020Article
- Studies on the interfacial behavior of DPPC/DPPG mixed monolayers in the presence of fluoxetine.Journal of molecular modeling · 2020Article
- Anti-inflammatory and cytotoxic evaluation of extracts from the flowering stage of Celosia argentea.BMC complementary medicine and therapies · 2020Article
- Effect of Tumor Relevant Acidic Environment in the Interaction of a N-hydroxyindole-2-Carboxylic Derivative with the Phospholipid Bilayer.Pharmaceutical research · 2018Article
- Effect of antimicrobial peptides from Galleria mellonella on molecular models of Leishmania membrane. Thermotropic and fluorescence anisotropy study.The Journal of antibiotics · 2018Article
- Predict drug permeability to blood-brain-barrier from clinical phenotypes: drug side effects and drug indications.Bioinformatics (Oxford, England) · 2017Article
- Selective effect of cell membrane on synaptic neurotransmission.Scientific reports · 2016Article
- Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Contact with many different biological membranes goes along the destiny of a drug after its systemic administration. From the circulating macrophage cells to the vessel endothelium, to more complex absorption barriers, the interaction of a biomolecule with these membranes largely affects its rate and time of biodistribution in the body and at the target sites. Therefore, investigating the phenomena occurring on the cell membranes, as well as their different interaction with drugs in the physiological or pathological conditions, is important to exploit the molecular basis of many diseases and to identify new potential therapeutic strategies. Of course, the complexity of the structure and functions of biological and cell membranes, has pushed researchers toward the proposition and validation of simpler two- and three-dimensional membrane models, whose utility and drawbacks will be discussed. This review also describes the analytical methods used to look at the interactions among bioactive compounds with biological membrane models, with a particular accent on the calorimetric techniques. These studies can be considered as a powerful tool for medicinal chemistry and pharmaceutical technology, in the steps of designing new drugs and optimizing the activity and safety profile of compounds already used in the therapy.
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Registered trials
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