Evidence map›Paper›PMID 21430562›Full record

ArticleJournal of hypertension2011

Secular trends in blood pressure during early-to-middle adulthood: the Fels Longitudinal Study.

Audrey C Choh, Ramzi W Nahhas, Miryoung Lee, Youn Su Choi, William C Chumlea, Dana L Duren, Richard J Sherwood, Bradford Towne, Roger M Siervogel, Ellen W Demerath and 1 more

Abstract read
In one paragraph

Article in Journal of hypertension, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Audrey C ChohLifespan Health Research Center, Wright State University Boonshoft School of Medicine, Dayton, Ohio 45420-4006, USA. audrey.choh@wright.edu
Ramzi W Nahhas
Miryoung Lee
Youn Su Choi
William C Chumlea
Dana L Duren
Richard J Sherwood
Bradford Towne
Roger M Siervogel
Ellen W Demerath
Stefan A Czerwinski

Funding

SUBCUTANEOUS FAT, BLOOD LIPIDS AND SUBSEQUENT OUTCOMER01HD012252 · NICHD · WRIGHT STATE UNIVERSITY · PI CZERWINSKI, STEFAN A. · 1985 to 2014
$17.3M
NICHD NIH HHS R01 HD012252NICHD NIH HHS R01-HD12252
6 · The paper itself

Abstract

backgroundSome studies have shown a decline in blood pressure (BP) over the second half of the twentieth century. However, the increasing prevalence of obesity may have opposite effects on recent cohorts.

methodUsing serial BP data from the Fels Longitudinal Study, we examined secular trends in mean BP, the rate of change in BP with age (slopes), and the influence of obesity (i.e., BMI) and height on these trends during young-to-middle adulthood. The study sample consisted of 970 adults, aged 18-40 years, who were born between 1920 and 1979. Participants were grouped into birth decade cohorts and had up to 11 serial measurements of SBP, DBP, and BMI. Sex-stratified mixed longitudinal analyses were used to identify cohort effects on mean BP at ages 19, 29, and 39 years, and on the rate of change in BP with age.

resultsFor both sexes, mean SBP did not vary significantly by birth cohort, before and after adjusting for height and BMI. Mean DBP exhibited a U-shaped secular trend even after adjusting for BMI and height that was influenced by age-by-cohort effects. By age 39 years, those born most recently had the highest mean DBP.

conclusionThere were cohort effects on the rate of change in DBP with age, but not on rate of SBP change. The most recent cohorts had higher rates of DBP change with age compared to the earlier cohorts. The secular trend was partially influenced by the trends in BMI.

Indexed as

Blood PressureAdolescentAdultCohort StudiesDiastoleFemaleHumansLongitudinal StudiesMaleSystoleYoung Adult

Identifiers

PMID21430562
PMCPMC3988666

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.