ReviewJournal of nutrigenetics and nutrigenomics2011
Nutrigenomics, vitamin D and cancer prevention.
Review in Journal of nutrigenetics and nutrigenomics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 54 citations in OpenAlex.
- Pooled it
- Genetic Variants Shaping Inter-individual Differences in Response to Dietary Intakes-A Narrative Review of the Case of Vitamins.Frontiers in nutrition · 2020Pooled it
- LC-N2G: a local consistency approach for nutrigenomics data analysis.BMC bioinformatics · 2020Article
- More Than Bone Health: The Many Roles for Vitamin D.Nutrients · 2020Article
- A New Palmitoylethanolamide Form Combined with Antioxidant Molecules to Improve Its Effectivess on Neuronal Aging.Brain sciences · 2020Article
- The Evolving Role of Multivitamin/Multimineral Supplement Use among Adults in the Age of Personalized Nutrition.Nutrients · 2018Review
- Biological effects of combined resveratrol and vitamin D3 on ovarian tissue.Journal of ovarian research · 2017Article
- Vitamin Pharmacogenomics: New Insight into Individual Differences in Diseases and Drug Responses.Genomics, proteomics & bioinformatics · 2017Review
- Protective effects of vitamin D3 on fimbrial cells exposed to catalytic iron damage.Journal of ovarian research · 2016Article
- Fast food fever: reviewing the impacts of the Western diet on immunity.Nutrition journal · 2014Review
- Cellular and molecular effects of vitamin D on carcinogenesis.Archives of biochemistry and biophysics · 2012Review
- Impaired vitamin D activation and association with CYP24A1 haplotypes in differentiated thyroid carcinoma.Thyroid : official journal of the American Thyroid Association · 2012Article
- Potential value of nutrigenomics in Crohn's disease.Nature reviews. Gastroenterology & hepatology · 2012Review
- Vitamin D intake and mental health-related quality of life in older women: the Iowa Women's Health Study.Maturitas · 2012Article
- The role of nutrition related genes and nutrigenetics in understanding the pathogenesis of cancer.Journal of microscopy and ultrastructureReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although there is growing epidemiological, preclinical and clinical evidence suggesting that low vitamin D intake, exposure and/or status is associated with an increased risk of various types of cancer, the optimum amount needed remains controversial. Furthermore, there is evidence that a U- or J-shaped response curve exist between 25(OH)D and certain cancers. Increasing information about the impact of genetic variation, especially polymorphisms that influence absorption, transport, metabolism and associated molecular targets, should help clarify inconsistencies in the data regarding vitamin D's effect on cancer risk. Rather than focusing on the main effects of a few variants of these genes alone, future studies need to consider gene-nutrient or environmental interactions. Nutrigenomics should clarify who might benefit and be placed at risk because of vitamin D exposure.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.