Evidence map›Paper›PMID 21430302›Full record

Trial reportCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2011

Evaluating the efficacy of lay health advisors for increasing risk-appropriate Pap test screening: a randomized controlled trial among Ohio Appalachian women.

Electra D Paskett, John M McLaughlin, Amy M Lehman, Mira L Katz, Cathy M Tatum, Jill M Oliveri

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  5. Assessing the Effectiveness of Cancer Screening Interventions Targeting Appalachian Populations: A Systematic Review.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2021
    Pooled it
  6. Pooled it
  7. Trial
  8. Trial
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  11. Review
  12. Cancer Screening in Appalachia: A Common-Sense Approach.International journal of behavioral medicine · 2025
    Article
  13. Review
  14. Article
  15. Building Capacity for Global Cancer Research: Existing Opportunities and Future Directions.Journal of cancer education : the official journal of the American Association for Cancer Education · 2021
    Article
  16. A Multi-level Model to Understand Cervical Cancer Disparities in Appalachia.Cancer prevention research (Philadelphia, Pa.) · 2020
    Article
  17. Article
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  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Electra D PaskettComprehensive Cancer Center, The Ohio State University, Columbus, OH 43201, USA. Electra.Paskett@osumc.edu
John M McLaughlin
Amy M Lehman
Mira L Katz
Cathy M Tatum
Jill M Oliveri

Funding

Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Tasleem J Padamsee · 1985 to 2026
$132.3M
University of Iowa Clinical and Translational Science Program (TL1)UL1RR025755 · NCRR · OHIO STATE UNIVERSITY · PI JACKSON, REBECCA D · 2008 to 2011
$26.3M
TRAINING AND CAREER DEVELOPMENTP50CA105632 · NCI · OHIO STATE UNIVERSITY · PI PASKETT, ELECTRA D. · 2003 to 2016
$17.2M
Patient Activation To Increase Colon Cancer ScreeningK07CA107079 · NCI · OHIO STATE UNIVERSITY · PI KATZ, MIRA L · 2005 to 2009
$783k
NCI NIH HHS K07 CA107079NCI NIH HHS P30 CA016058NCI NIH HHS P50 CA105632NCRR NIH HHS UL1 RR025755NCRR NIH HHS UL1-RR025755
6 · The paper itself

Abstract

backgroundCervical cancer is a significant health disparity among women in Ohio Appalachia. The goal of this study was to evaluate the efficacy of a lay health advisor (LHA) intervention for improving Papanicolaou (Pap) testing rates, to reduce cervical cancer, among women in need of screening.

methodsWomen from 14 Ohio Appalachian clinics in need of a Pap test were randomized to receive either usual care or an LHA intervention over a 10-month period. The intervention consisted of two in-person visits with an LHA, two phone calls, and four postcards. Both self-report and medical record review (MRR) data (primary outcome) were analyzed.

resultsOf the 286 women, 145 and 141 were randomized to intervention and usual care arms, respectively. According to MRR, more women in the LHA arm had a Pap test by the end of the study compared with those randomized to usual care (51.1% vs. 42.0%; OR = 1.44, 95% CI: 0.89-2.33; P = 0.135). Results of self-report were more pronounced (71.3% vs. 54.2%; OR = 2.10, 95% CI: 1.22-3.61; P = 0.008).

conclusionsAn LHA intervention showed some improvement in the receipt of Pap tests among Ohio Appalachian women in need of screening. Although biases inherent in using self-reports of screening are well known, this study also identified biases in using MRR data in clinics located in underserved areas. IMPACT: LHA interventions show promise for improving screening behaviors among nonadherent women from underserved populations.

Indexed as

Papanicolaou TestWomen's Health ServicesAdolescentAdultAppalachian RegionCommunity Health WorkersFemaleHumansMass ScreeningMiddle AgedOhioResearch DesignRisk AssessmentUterine Cervical NeoplasmsVaginal SmearsWorkforce

Identifiers

PMID21430302
PMCPMC3089673

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.