ArticleFrontiers in neural circuits2011
Receptive Field Remodeling Induced by Skin Stimulation in Cerebellar Neurons in vivo.
Article in Frontiers in neural circuits, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 31 citations in OpenAlex.
- Beyond synaptic plasticity: a summary of a linear model of the cerebellar locomotor computation.Frontiers in neural circuits · 2026Review
- Intrinsic and synaptic determinants of receptive field plasticity in Purkinje cells of the mouse cerebellum.Nature communications · 2024Article
- Afferent convergence to a shared population of interneuron AMPA receptors.Nature communications · 2023Article
- Gating by Memory: a Theory of Learning in the Cerebellum.Cerebellum (London, England) · 2022Article
- How and Why the Cerebellum Recodes Input Signals: An Alternative to Machine Learning.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2022Article
- Molecular layer interneurons in the cerebellum encode for valence in associative learning.Nature communications · 2020Article
- Biological data questions the support of the self inhibition required for pattern generation in the half center model.PloS one · 2020Article
- Cerebellar learning using perturbations.eLife · 2018Article
- No Medium-Term Spinocerebellar Input Plasticity in Deep Cerebellar Nuclear Neurons In Vivo?Cerebellum (London, England) · 2017Article
- Cerebellar physiology: links between microcircuitry properties and sensorimotor functions.The Journal of physiology · 2017Review
- Cerebellar Synaptic Plasticity and the Credit Assignment Problem.Cerebellum (London, England) · 2016Review
- Redefining the cerebellar cortex as an assembly of non-uniform Purkinje cell microcircuits.Nature reviews. Neuroscience · 2015Review
- A Model of In vitro Plasticity at the Parallel Fiber-Molecular Layer Interneuron Synapses.Frontiers in computational neuroscience · 2015Article
- Specific relationship between excitatory inputs and climbing fiber receptive fields in deep cerebellar nuclear neurons.PloS one · 2014Article
- An adaptive filter model of cerebellar zone C3 as a basis for safe limb control?The Journal of physiology · 2013Review
- Cross-correlations between pairs of neurons in cerebellar cortex in vivo.Neural networks : the official journal of the International Neural Network Society · 2013Article
- Ontogeny of trace eyeblink conditioning to shock-shock pairings in the rat pup.Behavioral neuroscience · 2013Article
- Cerebellar cortical neuron responses evoked from the spinal border cell tract.Frontiers in neural circuits · 2013Article
- Parallel fiber and climbing fiber responses in rat cerebellar cortical neurons in vivo.Frontiers in systems neuroscience · 2013Article
- Translational approach to behavioral learning: lessons from cerebellar plasticity.Neural plasticity · 2013Review
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The receptive field of a neuron reflects its function. For example, for parallel fiber (PF) inputs in C3 zone the cerebellar cortex, the excitatory and inhibitory receptive fields of a Purkinje cell (PC) have different locations, and each location has a specific relationship to the location of the climbing fiber (CF) receptive field of the PC. Previous studies have shown that this pattern of input connectivity to the PC and its afferent inhibitory interneurons can be fundamentally disrupted by applying direct electrical stimulation to the PFs, paired or unpaired with CF activation, with protocols that induce plasticity in these synapses. However, afferent fiber stimulation, which is typically used in experimental studies of plasticity, set up highly artificial input patterns at the level of the recipient cells, raising the issue that these forms of plasticity potentially may not occur under more natural input patterns. Here we used skin stimulation to set up spatiotemporally more realistic afferent input patterns in the PFs to investigate whether these input patterns are also capable of inducing synaptic plasticity using similar protocols that have previously been described for direct PF stimulation. We find that receptive field components can be added to and removed from PCs and interneurons following brief periods of skin stimulation. Following these protocols, the receptive fields of mossy fibers were unchanged. These findings confirm that previously described plasticity protocols may have a functional role also for more normal patterns of afferent input.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.