Evidence map›Paper›PMID 21427362›Full record

ArticleCirculation. Cardiovascular imaging2011

Bright-blood T2-weighted MRI has higher diagnostic accuracy than dark-blood short tau inversion recovery MRI for detection of acute myocardial infarction and for assessment of the ischemic area at risk and myocardial salvage.

Alexander R Payne, Matthew Casey, John McClure, Ross McGeoch, Aengus Murphy, Rosemary Woodward, Andrew Saul, Xiaoming Bi, Sven Zuehlsdorff, Keith G Oldroyd and 2 more

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Circulation. Cardiovascular imaging, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
11.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 110 citations in OpenAlex.

  1. Trial
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  7. Review
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  9. Article
  10. Black-Blood Contrast in Cardiovascular MRI.Journal of magnetic resonance imaging : JMRI · 2022
    Review
  11. Article
  12. Article
  13. Assessment of intramyocardial hemorrhage with dark-blood T2*-weighted cardiovascular magnetic resonance.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2021
    Article
  14. Observational
  15. Observational
  16. Article
  17. Review
  18. Cardiac T2 mapping: robustness and homogeneity of standardized in-line analysis.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2020
    Article
  19. TJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2019
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Alexander R PayneWest of Scotland Heart and Lung Centre, Golden Jubilee National Hospital, Glasgow, Scotland, United Kingdom.
Matthew Casey
John McClure
Ross McGeoch
Aengus Murphy
Rosemary Woodward
Andrew Saul
Xiaoming Bi
Sven Zuehlsdorff
Keith G Oldroyd
Niko Tzemos
Colin Berry
University of Glasgow · GB

Funding

Chief Scientist Office CZB/4/572Chief Scientist Office SCD/01
6 · The paper itself

Abstract

backgroundT2-Weighted MRI reveals myocardial edema and enables estimation of the ischemic area at risk and myocardial salvage in patients with acute myocardial infarction (MI). We compared the diagnostic accuracy of a new bright-blood T2-weighted with a standard black blood T2-weighted MRI in patients with acute MI. METHODS AND

resultsA breath-hold, bright-blood T2-weighted, Acquisition for Cardiac Unified T2 Edema pulse sequence with normalization for coil sensitivity and a breath-hold T2 dark-blood short tau inversion recovery sequence were used to depict the area at risk in 54 consecutive acute MI patients. Infarct size was measured on gadolinium late contrast enhancement images. Compared with dark-blood T2-weighted MRI, consensus agreements between independent observers for identification of myocardial edema were higher with bright-blood T2-weighted MRI when evaluated per patient (P<0.001) and per segment of left ventricle (P<0.001). Compared with bright-blood T2-weighted MRI, dark-blood T2-weighted MRI underestimated the area at risk compared with infarct size (P<0.001). The 95% limits of agreement for interobserver agreements for the ischemic area at risk and myocardial salvage were wider with dark-blood T2-weighted MRI than with bright-blood T2-weighted MRI. Bright blood enabled more accurate identification of the culprit coronary artery with correct identification in 94% of cases compared with 61% for dark blood (P<0.001).

conclusionsBright-blood T2-weighted MRI has higher diagnostic accuracy than dark-blood T2-weighted MRI. Additionally, dark-blood T2-weighted MRI may underestimate area at risk and myocardial salvage.

Indexed as

BloodCoronary AngiographyEdema, CardiacFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedMyocardial InfarctionMyocardial IschemiaMyocardiumObserver Variation

Identifiers

PMID21427362
OpenAlexW2162117866

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.