ArticlePlant physiology2011
COP1-mediated degradation of BBX22/LZF1 optimizes seedling development in Arabidopsis.
Article in Plant physiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers, 1 of them a synthesis that pooled it.
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Who cites it
78 citing papers in PubMed, 1 synthesis or guideline pooled it, 127 citations in OpenAlex.
- Precise scheduling of B-box transcription factors: the core network for balancing plant growth, metabolism and stress resistance.Frontiers in plant science · 2026Pooled it
- MdBBX47, a B-box transcription factor directly and indirectly regulates ALA-induced anthocyanin accumulation in apple.BMC plant biology · 2026Article
- Genome-Wide Identification of the Double B-Box (DBB) Family in Three Cotton Species and Functional Analysis ofPlants (Basel, Switzerland) · 2025Article
- Article
- ABA-GA antagonism and modular gene networks cooperatively drive acquisition of desiccation tolerance in perilla seeds.Frontiers in plant science · 2025Article
- Genome-Wide Identification, Characterization and Expression Patterns of the DBB Transcription Factor Family Genes in Wheat.International journal of molecular sciences · 2024Article
- Transcription factors LvBBX24 and LvbZIP44 coordinated anthocyanin accumulation in response to light in lily petals.Horticulture research · 2024Article
- Genome-Wide Identification of B-Box Family Genes and Their Potential Roles in Seed Development under Shading Conditions in Rapeseed.Plants (Basel, Switzerland) · 2024Article
- Genome-wide association study for yield and quality of granulated cassava processed product.The plant genome · 2024Article
- Genome-Wide Identification of B-Box Gene Family and Candidate Light-Related Member Analysis of Tung Tree (International journal of molecular sciences · 2024Article
- Natural genetic variation in GLK1-mediated photosynthetic acclimation in response to light.BMC plant biology · 2024Article
- AtBBX29 integrates photomorphogenesis and defense responses in Arabidopsis.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2023Article
- SUPPRESSOR OF PHYTOCHROME B-4 #3 reduces the expression of PIF-activated genes and increases expression of growth repressors to regulate hypocotyl elongation in short days.BMC plant biology · 2022Article
- Arabidopsis B-box transcription factors BBX20-22 promote UVR8 photoreceptor-mediated UV-B responses.The Plant journal : for cell and molecular biology · 2022Article
- Two B-Box Proteins, MaBBX20 and MaBBX51, Coordinate Light-Induced Anthocyanin Biosynthesis in Grape Hyacinth.International journal of molecular sciences · 2022Article
- Genetic Dissection of Light-Regulated Adventitious Root Induction inInternational journal of molecular sciences · 2022Article
- Noise reduction by upstream open reading frames.Nature plants · 2022Article
- Article
- BBX16 mediates the repression of seedling photomorphogenesis downstream of the GUN1/GLK1 module during retrograde signalling.The New phytologist · 2022Article
- Phytochrome interacting factor MdPIF7 modulates anthocyanin biosynthesis and hypocotyl growth in apple.Plant physiology · 2022Article
18 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Light regulates multiple aspects of growth and development in plants. Transcriptomic changes govern the expression of signaling molecules with the perception of light. Also, the 26S proteasome regulates the accumulation of positive and negative regulators for optimal growth of Arabidopsis (Arabidopsis thaliana) in the dark, light, or light/dark cycles. BBX22, whose induction is both light regulated and HY5 dependent, is a positive regulator of deetiolation in Arabidopsis. We found that during skotomorphogenesis, the expression of BBX22 needs to be tightly regulated at both transcriptional and posttranslational levels. During photomorphogenesis, the expression of BBX22 transiently accumulates to execute its roles as a positive regulator. BBX22 protein accumulates to a higher level under short-day conditions and functions to inhibit hypocotyl elongation. The proteasome-dependent degradation of BBX22 protein is tightly controlled even in plants overexpressing BBX22. An analysis of BBX22 degradation kinetics shows that the protein has a short half-life under both dark and light conditions. COP1 mediates the degradation of BBX22 in the dark. Although dispensable in the dark, HY5 contributes to the degradation of BBX22 in the light. The constitutive photomorphogenic development of the cop1 mutant is enhanced in cop1BBX22ox plants, which show a short hypocotyl, high anthocyanin accumulation, and expression of light-responsive genes. Exaggerated light responsiveness is also observed in cop1BBX22ox seedlings grown under short-day conditions. Therefore, the proper accumulation of BBX22 is crucial for plants to maintain optimal growth when grown in the dark as well as to respond to seasonal changes in daylength.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.