ReviewVascular medicine (London, England)2011
Acrocyanosis: the Flying Dutchman.
Review in Vascular medicine (London, England), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 84 citations in OpenAlex.
- Is Achenbach's syndrome a surgical emergency? A systematic review.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2016Pooled it
- Review
- Drug-Induced Acrocyanosis: Highlighting Venlafaxine as a Potential Culprit.Clinical case reports · 2025Article
- Acrocyanosis: The Least Known Acrosyndrome Revisited With a Dermatologic Perspective.Dermatology research and practice · 2025Review
- Article
- Acrocyanosis as a rare presentation of drug-induced cutaneous vasculitis: a case report.BMC rheumatology · 2024Article
- Raynaud's Phenomenon: A Current Update on Pathogenesis, Diagnostic Workup, and Treatment.Vascular specialist international · 2024Review
- Part II: Cutaneous manifestations of peripheral vascular disease.Journal of the American Academy of Dermatology · 2023Review
- Similarities and differences regarding acute anorexia nervosa and semi-starvation: does behavioral thermoregulation play a central role?Frontiers in behavioral neuroscience · 2023Article
- Pseudoacrocyanosis: a case for telemedicine in rheumatology.RMD open · 2022Article
- Article
- [Functional vascular acrosyndromes].Innere Medizin (Heidelberg, Germany) · 2022Review
- The position of geochemical variables as causal co-factors of diseases of unknown aetiology.SN applied sciences · 2022Review
- Primary acrocyanosis.Journal of general and family medicine · 2021Article
- A visually striking case of primary acrocyanosis: A rare cause of the blue digit.The American journal of emergency medicine · 2021Article
- The Central Role of Hypothermia and Hyperactivity in Anorexia Nervosa: A Hypothesis.Frontiers in behavioral neuroscience · 2021Article
- The case of a painful blue thumb.JAAD case reports · 2020Article
- Infrared thermography in children: a reliable tool for differential diagnosis of peripheral microvascular dysfunction and Raynaud's phenomenon?Pediatric rheumatology online journal · 2019Article
- Vascular acrosyndromes in young adult population. Definition of clinical symptoms and connections to joint hypermobility.Clinical rheumatology · 2019Observational
- Acrocyanosis - A Symptom with Many Facettes.Open access Macedonian journal of medical sciences · 2018Review
Corrections and comments
- Erratum issued
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Acrocyanosis is symmetric, painless, discoloration of different shades of blue in the distal parts of the body that is marked by symmetry, relative persistence of the skin color changes with aggravation by cold exposure, and frequent association with local hyperhidrosis of hands and feet. Described over a century ago and despite seeming familiarity, it remains a poorly understood condition that shares much in clinical presentation with other conditions characterized by skin color changes in the distal parts of the body. The diagnosis remains mostly clinical, and pathological mechanisms vary suggesting that acrocyanosis may not be a single entity. We performed an extensive literature review to summarize existing knowledge about the demographics, pathology, diagnosis, and treatment of this condition.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.