Evidence map›Paper›PMID 21424686›Full record

ArticleJournal of industrial microbiology & biotechnology2011

Cinnamic acid production using Streptomyces lividans expressing phenylalanine ammonia lyase.

Shuhei Noda, Takaya Miyazaki, Takanori Miyoshi, Michiru Miyake, Naoko Okai, Tsutomu Tanaka, Chiaki Ogino, Akihiko Kondo

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Journal of industrial microbiology & biotechnology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 56 citations in OpenAlex.

  1. Article
  2. Bioconversion of L-Tyrosine intoCurrent issues in molecular biology · 2024
    Article
  3. Styrene Production in Genetically EngineeredBiotech (Basel (Switzerland)) · 2024
    Article
  4. Article
  5. Review
  6. Review
  7. Rational Engineering of Phenylalanine Accumulation inFrontiers in bioengineering and biotechnology · 2019
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Production of Cinnamic and p-Hydroxycinnamic Acids in Engineered Microbes.Frontiers in bioengineering and biotechnology · 2015
    Review
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Shuhei NodaDepartment of Chemical Science and Engineering, Graduate School of Engineering, Kobe University, 1-1 Rokkodai, Nada, Kobe, 657-8501, Japan.
Takaya Miyazaki
Takanori Miyoshi
Michiru Miyake
Naoko Okai
Tsutomu Tanaka
Chiaki Ogino
Akihiko Kondo
Kobe University · JPTeijin (Japan) · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cinnamic acid production was demonstrated using Streptomyces as a host. A gene encoding phenylalanine ammonia lyase (PAL) from Streptomyces maritimus was introduced into Streptomyces lividans, and its expression was confirmed by Western blot analysis. After 4 days cultivation using glucose as carbon source, the maximal level of cinnamic acid reached 210 mg/L. When glycerol (30 g/L) was used as carbon source, the maximal level of produced cinnamic acid reached 450 mg/L. In addition, using raw starch, xylose or xylan as carbon source, the maximal level of cinnamic acid reached 460, 300, and 130 mg/L, respectively. We demonstrated that S. lividans has great potential to produce cinnamic acid as well as other aromatic compounds.

Indexed as

CinnamatesGlycerolPhenylalanine Ammonia-LyaseStreptomycesStreptomyces lividansCinnamatescinnamic acidGlycerolPhenylalanine Ammonia-Lyase

Identifiers

PMID21424686
OpenAlexW2114660266

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.