ReviewCurrent diabetes reports2011
Peripheral arterial disease in diabetes: is there a role for genetics?
Review in Current diabetes reports, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 18 citations in OpenAlex.
- Assessment of Blood-Count-Derived Biomarkers, Homocysteine Levels, MTHFR Mutation, and Clinical Manifestations in Severe Peripheral Artery Disease.Biomedicines · 2026Article
- Article
- Outcomes after first-time lower extremity revascularization for chronic limb-threatening ischemia in insulin-dependent diabetic patients.Journal of vascular surgery · 2018Article
- Outcomes after first-time lower extremity revascularization for chronic limb-threatening ischemia between patients with and without diabetes.Journal of vascular surgery · 2018Article
- Role of genetics in peripheral arterial disease outcomes; significance of limb-salvage quantitative locus-1 genes.Experimental biology and medicine (Maywood, N.J.) · 2018Review
- Modulation of miR29a improves impaired post-ischemic angiogenesis in hyperglycemia.Experimental biology and medicine (Maywood, N.J.) · 2017Article
- BAG3 (Bcl-2-Associated Athanogene-3) Coding Variant in Mice Determines Susceptibility to Ischemic Limb Muscle Myopathy by Directing Autophagy.Circulation · 2017Article
- Diminished force production and mitochondrial respiratory deficits are strain-dependent myopathies of subacute limb ischemia.Journal of vascular surgery · 2017Article
- Fibroblast Growth Factor-9 Activates c-Kit Progenitor Cells and Enhances Angiogenesis in the Infarcted Diabetic Heart.Oxidative medicine and cellular longevity · 2016Article
- Mitochondrial Regulation of the Muscle Microenvironment in Critical Limb Ischemia.Frontiers in physiology · 2015Review
- High prevalence of lower extremity peripheral artery disease in type 2 diabetes patients with proliferative diabetic retinopathy.PloS one · 2015Article
- Systematic reviews and meta-analyses for more profitable strategies in peripheral artery disease.Annals of medicine · 2014Review
- Genetics of peripheral artery disease.Circulation · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Atherosclerotic occlusion of vessels outside of the heart is commonly referred to as peripheral arterial disease (PAD). The lower extremity is the most common site of PAD and its development is associated with the same risk factors involved in general atherosclerosis. However, there is emerging evidence that other risk factors may play a key role in the development of PAD. Over the past decade polymorphism in a number of genes has been shown to contribute to the risk of developing PAD. These genes can be classified into proartherosclerosis or proatherothrombosis based on the known gene function. Moreover, they can be categorized as "novel" polymorphism when the function of the genes is not known or when the specific gene within an associated genetic locus is not known. It is intriguing that not only are gene polymorphisms associated with PAD being identified, but more recently studies are now finding gene polymorphisms that may be important in development of this syndrome only in the contest of certain environmental factors such as diabetes. Currently how these gene-environment interactions contribute to the pathogenesis of PAD is poorly understood but will likely play a critical role in future understanding of this complex disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.