ArticleMycopathologia2011
Paracoccidioidomycosis in a dog: case report of generalized lymphadenomegaly.
Article in Mycopathologia, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 51 citations in OpenAlex.
- Disseminated paracoccidioidomycosis in a black lion tamarin (Leontopithecus chrysopygus) confirmed by histopathology, molecular diagnostics and phylogenetic analysis of DNA from FFPE tissues.Veterinary research communications · 2026Article
- The Zoonotic Potential of Fungal Pathogens: Another Dimension of the One Health Approach.Diagnostics (Basel, Switzerland) · 2024Review
- An atypical case of chronic paracoccidioidomycosis in a dog caused by a fungus from the Paracoccidioides brasiliensis complex.Veterinary research communications · 2024Article
- The Effect of Geoclimatic Factors on the Distribution of Paracoccidioidomycosis in Mato Grosso do Sul, Brazil.Journal of fungi (Basel, Switzerland) · 2024Article
- Epidemiologic, Clinical and Immunological Consequences of Co-Infections during Canine Leishmaniosis.Animals : an open access journal from MDPI · 2021Review
- Molecular epidemiology of Paracoccidiodes spp. recovered from patients with paracoccidioidomycosis in a teaching hospital from Minas Gerais State of Brazil.PLoS neglected tropical diseases · 2021Article
- Article
- Phylogenetic Species ofJournal of fungi (Basel, Switzerland) · 2020Article
- Thinking in paracoccidioidomycosis: a delayed diagnosis of a neglected tropical disease, case report and review of clinical reports and eco-epidemiologic data from Colombia since the 2000.BMC infectious diseases · 2020Review
- Fungal infections in animals: a patchwork of different situations.Medical mycology · 2018Review
- Serological Evidence of Infection by Paracoccidioides brasiliensis in Dogs with Leishmaniasis.Mycopathologia · 2017Article
- Paracoccidioides brasiliensis-associated dermatitis and lymphadenitis in a dog.Mycopathologia · 2017Article
- New Trends in Paracoccidioidomycosis Epidemiology.Journal of fungi (Basel, Switzerland) · 2017Review
- Paracoccidioidomycosis: Current Perspectives from Brazil.The open microbiology journal · 2017Review
- Article
- Serological Investigation into Paracoccidioides brasiliensis Infection in Dogs from Southern Rio Grande do Sul, Brazil.Mycopathologia · 2016Article
- Coccidioidomycosis in Biopsies with Presumptive Diagnosis of Malignancy in Dogs: Report of Three Cases and Comparative Discussion of Published Reports.Mycopathologia · 2016Article
- Paracoccidioides brasiliensis Infection in Small Wild Mammals.Mycopathologia · 2015Article
- EPIDEMIOLOGY OF PARACOCCIDIOIDOMYCOSIS.Revista do Instituto de Medicina Tropical de Sao Paulo · 2015Article
- Paracoccidioides species complex: ecology, phylogeny, sexual reproduction, and virulence.PLoS pathogens · 2014Article
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Paracoccidioidomycosis (PCM) is a severe systemic mycosis, endemic in Latin America and highly prevalent in Brazil, where it ranks eighth as a mortality cause among infectious and parasitic diseases in humans. The disease in animals has been little explored. It is observed that armadillos can harbor the fungus at high frequencies, although the active disease has not been well documented in this wild mammal. Dogs are susceptible to experimental infection, and the naturally acquired PCM-disease was reported only recently in a dog from Brazil. The present work reports the second case of naturally acquired PCM in a 6-year-old female dog that presented emaciation, lymphadenomegaly, and hepatosplenomegaly. Biochemical and pulmonary radiographic evaluation did not reveal any abnormalities. PCM was diagnosed by clinical findings, culturing, immunohistochemistry, and histopathology of popliteal lymph node. The fungus was recovered from popliteal lymph node, and the molecular analysis showed respective sequencing similarities of 99 and 100% for 803 nucleotides of the Gp43 gene and 592 nucleotides from the ITS-5.8S region of Paracoccidioides brasiliensis. Immunohistochemistry revealed severe lymphadenitis and presented numerous yeasts, which reacted against the gp43 antibody. Histopathology revealed a severe granulomatous lymphadenitis associated with numerous single or multiple budding yeasts. After diagnosis, the dog was successfully treated with itraconazol for 2 years. Veterinarians should be aware of the importance of considering PCM for differential diagnosis, especially in dogs from PCM-endemic areas, whose monophagocytic system involvement is evident.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.