Evidence map›Paper›PMID 21424524›Full record

ArticlePediatric nephrology (Berlin, Germany)2011

No difference in meeting hemoglobin and albumin targets for dialyzed children with urologic disorders.

Rachel M Lestz, Meredith Atkinson, Barbara Fivush, Susan L Furth

Abstract readComparative Study
In one paragraph

Article in Pediatric nephrology (Berlin, Germany), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 94% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Rachel M LestzDivision of Pediatric Nephrology, Johns Hopkins University, 200 N. Wolfe St., Baltimore, MD 21287, USA. rmlestz@gmail.com
Meredith Atkinson
Barbara Fivush
Susan L Furth
Johns Hopkins University · USChildren's Hospital of Philadelphia · US

Funding

RENAL DISEASE EPIDEMIOLOGY TRAINING GRANTT32DK007732 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI CREWS, DEIDRA CANDICE · 1995 to 2024
$7.7M
Patient Oriented Research in Pediatric Kidney DiseaseK24DK078737 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI FURTH, SUSAN L. · 2007 to 2016
$1.6M
Hepcidin and Anemia in Children: Mechanisms and ModifiersK23DK084116 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI ATKINSON, MEREDITH ANN · 2011 to 2015
$855k
NIDDK NIH HHS K23 DK084116NIDDK NIH HHS K24 DK078737NIDDK NIH HHS T32 DK007732
6 · The paper itself

Abstract

Urologic disorders are the most common cause of chronic kidney disease in children. To determine whether children with urologic etiology of end-stage renal disease (ESRD) fare better than children with ESRD from other causes while on dialysis, we conducted a cross-sectional study of children <18 years receiving peritoneal and hemodialysis in the United States using data from the Centers for Medicare & Medicaid Services 2005 ESRD CPM Project. We compared baseline demographics and the study groups. In multivariate logistic regression analysis of 1,286 subjects, we assessed whether children with urologic disorders had a higher odds of meeting adult KDOQI targets for hemoglobin levels ≥11 g/dl and albumin ≥3.5 BCG/3.2 BCP g/dl. We conducted a subset analysis of 1,136 patients to examine the impact of erythropoietin on hemoglobin targets. Our results did not reveal differences in achievement of adult hemoglobin targets (adjusted OR: 1.27; p value 0.09; CI: 0.97-1.66) or in the subset analysis with erythropoietin (adjusted OR: 1.32; p value 0.06; CI: 0.98-1.78) or albumin targets (adjusted OR: 1.22; p value 0.21; CI: 0.90-1.65) in adjusted analyses. Due to our study's limitations, it is difficult to determine whether this may result from treatment prior to dialysis initiation or treatment effect of dialysis rather than underlying diagnosis.

Indexed as

Peritoneal DialysisRenal DialysisAdolescentBiomarkersCenters for Medicare and Medicaid Services, U.S.ChildChild, PreschoolChi-Square DistributionCross-Sectional StudiesErythropoietinFemaleGuideline AdherenceHematinicsHemoglobinsHumansKidney Failure, ChronicBiomarkersErythropoietinHematinicsHemoglobinsSerum Albumin

Identifiers

PMID21424524
PMCPMC5739035
OpenAlexW1975311953

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.