Evidence map›Paper›PMID 21423681›Full record

ArticleEnzyme research2011

The Roles of ADAMs Family Proteinases in Skin Diseases.

Masakazu Kawaguchi, Vincent J Hearing

Open access · diamondAbstract read
In one paragraph

Article in Enzyme research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Article
  3. Autocrine/Paracrine Loop Between SCFFrontiers in immunology · 2022
    Article
  4. Article
  5. Review
  6. Characterization of Burn Eschar Pericytes.Journal of clinical medicine · 2020
    Article
  7. Proteases in Pemphigoid Diseases.Frontiers in immunology · 2019
    Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Masakazu KawaguchiLaboratory of Cell Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20814, USA.
Vincent J Hearing
National Cancer Institute · US

Funding

Characterization of Pigmentary Disorders and Melanoma TargetingZIABC010785 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI HEARING, VINCENT J · 2009 to 2014
$3.0M
6 · The paper itself

Abstract

A disintegrin and metalloproteinases (ADAMs) are members of a new gene family of transmembrane and secreted proteins, which belong to the zinc proteinase superfamily. These molecules are involved in various biological events such as cell adhesion, cell fusion, cell migration, membrane protein shedding, and proteolysis. Growing evidence now attests to the potential involvement of ADAMs proteinases in diverse processes such as skin wound healing, inflammation, pigmentation, tumor development, cell proliferation, and metastasis. This paper focuses on the roles of ADAMs proteinases in a wide variety of skin diseases.

Identifiers

PMID21423681
PMCPMC3057028
OpenAlexW2039109654

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.