ArticleEvidence-based complementary and alternative medicine : eCAM2011
Effects of phenolic compounds of fermented thai indigenous plants on oxidative stress in streptozotocin-induced diabetic rats.
Article in Evidence-based complementary and alternative medicine : eCAM, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 55 citations in OpenAlex.
- Article
- Chamomile Extract Reduces Cardiac Toxicity in Female Mice with Ehrlich Solid Carcinoma.Cell biochemistry and biophysics · 2025Article
- Integrated in vitro, in silico, and in vivo approaches to elucidate the antidiabetic mechanisms of Cicer arietinum and Hordeum vulgare extract and secondary metabolites.Scientific reports · 2025Article
- Bacteriocin-ProducingFoods (Basel, Switzerland) · 2023Article
- Phytomedicinal therapeutics for male infertility: critical insights and scientific updates.Journal of natural medicines · 2022Review
- Antidiabetic effects of the ethanolic extract ofFood science & nutrition · 2021Article
- Effects of supplemental Bacillus subtilis, injectable vitamin E plus selenium, or both on health parameters during the transition period in dairy cows in a tropical environment.Tropical animal health and production · 2021Article
- Effects of FermentedJournal of nutrition and metabolism · 2021Article
- The Underlying Mechanisms of Curcumin Inhibition of Hyperglycemia and Hyperlipidemia in Rats Fed a High-Fat Diet Combined With STZ Treatment.Molecules (Basel, Switzerland) · 2020Article
- The Effects of Folic Acid Administration on Cardiac Oxidative Stress and Cardiovascular Biomarkers in Diabetic Rats.Oxidative medicine and cellular longevity · 2019Article
- Characteristics and multi‑lineage differentiation of bone marrow mesenchymal stem cells derived from the Tibetan mastiff.Molecular medicine reports · 2018Article
- Attenuation of Oxidative Stress and Inflammation by Portulaca oleracea in Streptozotocin-Induced Diabetic Rats.Journal of evidence-based complementary & alternative medicine · 2017Article
- The Effect of Green Tea Extract on Oxidative Stress and Spatial Learning in Streptozotocin-diabetic Rats.Iranian journal of pharmaceutical research : IJPR · 2017Article
- A current update on the phytopharmacological aspects of Houttuynia cordata Thunb.Pharmacognosy reviews · 2014Review
- S-allylcysteine Improves Streptozotocin-Induced Alterations of Blood Glucose, Liver Cytochrome P450 2E1, Plasma Antioxidant System, and Adipocytes Hormones in Diabetic Rats.International journal of endocrinology and metabolism · 2013Article
- Dracaena arborea alleviates ultra-structural spermatogenic alterations in streptozotocin-induced diabetic rats.BMC complementary and alternative medicine · 2013Article
- Hypoglycemic effect of Carica papaya leaves in streptozotocin-induced diabetic rats.BMC complementary and alternative medicine · 2012Article
- The hypoglycemic effect of the kelp on diabetes mellitus model induced by alloxan in rats.International journal of molecular sciences · 2012Article
- Catechin Treatment Ameliorates Diabetes and Its Complications in Streptozotocin-Induced Diabetic Rats.Dose-response : a publication of International Hormesis SocietyArticle
- Immunomodulatory and antioxidant effects of saffron aqueous extract (Crocus sativus L.) on streptozotocin-induced diabetes in rats.Indian heart journalArticle
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We investigated the effects of antioxidant activity of fermentation product (FP) of five Thai indigenous products on oxidative stress in Wistar rats with streptozotocin (STZ)-induced diabetes type II. The rats were fed with placebo and with the FP (2 and 6 mL/kg body weight/day) for 6 weeks. Rutin, pyrogallol and gallic acid were main compounds found in the FP. Plasma glucose levels in diabetic rats receiving the higher dose of the FP increased less when compared to the diabetic control group as well as the group receiving the lower FP dose (13.1%, 29%, and 21.1%), respectively. A significant dose-dependent decrease in plasma levels of thiobarbituric acid reactive substance (P < .05) was observed. In addition, the doses of 2 and 6 mL FP/kg/day decreased the levels of erythrocyte ROS in diabetic rats during the experiment, but no difference was observed when compared to the untreated diabetic rat group. Results imply that FP decreased the diabetes-associated oxidative stress to a large extent through the inhibition of lipid peroxidation. The FP also improved the abnormal glucose metabolism slightly but the difference was not statistically significant. Thus, FP may be a potential therapeutic agent by reducing injury caused by oxidative stress associated with diabetes.
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