ArticlePloS one2011
High temperature and bacteriophages can indirectly select for bacterial pathogenicity in environmental reservoirs.
Article in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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Who cites it
46 citing papers in PubMed.
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- Spontaneous mutations in hlyD and tuf genes result in resistance of Dickeya solani IPO 2222 to phage ϕD5 but cause decreased bacterial fitness and virulence in planta.Scientific reports · 2023Article
- Sub-optimal temperatures lead to altered expression of stress-related genes and increased 'CFrontiers in insect science · 2023Article
- The effect of a temperature-sensitive prophage on the evolution of virulence in an opportunistic bacterial pathogen.Molecular ecology · 2022Article
- Growth rate determines prokaryote-provirus network modulated by temperature and host genetic traits.Microbiome · 2022Article
- Rich resource environment of fish farms facilitates phenotypic variation and virulence in an opportunistic fish pathogen.Evolutionary applications · 2022Article
- Interactions between bacterial and phage communities in natural environments.Nature reviews. Microbiology · 2022Review
- Occurrence of genes associated with virulence in Escherichia coli isolates from chicken carcasses at different stages of processing at a slaughterhouse.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2021Article
- Mediterranean Aquaculture in a Changing Climate: Temperature Effects on Pathogens and Diseases of Three Farmed Fish Species.Pathogens (Basel, Switzerland) · 2021Review
- Climatic Alterations Influence Bacterial Growth, Biofilm Production and Antimicrobial Resistance Profiles inAntibiotics (Basel, Switzerland) · 2021Article
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- New Genotype ofFrontiers in microbiology · 2021Article
- Adapting a Phage to Combat Phage Resistance.Antibiotics (Basel, Switzerland) · 2020Article
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9 authors.
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Abstract
The coincidental evolution hypothesis predicts that traits connected to bacterial pathogenicity could be indirectly selected outside the host as a correlated response to abiotic environmental conditions or different biotic species interactions. To investigate this, an opportunistic bacterial pathogen, Serratia marcescens, was cultured in the absence and presence of the lytic bacteriophage PPV (Podoviridae) at 25°C and 37°C for four weeks (N = 5). At the end, we measured changes in bacterial phage-resistance and potential virulence traits, and determined the pathogenicity of all bacterial selection lines in the Parasemia plantaginis insect model in vivo. Selection at 37°C increased bacterial motility and pathogenicity but only in the absence of phages. Exposure to phages increased the phage-resistance of bacteria, and this was costly in terms of decreased maximum population size in the absence of phages. However, this small-magnitude growth cost was not greater with bacteria that had evolved in high temperature regime, and no trade-off was found between phage-resistance and growth rate. As a result, phages constrained the evolution of a temperature-mediated increase in bacterial pathogenicity presumably by preferably infecting the highly motile and virulent bacteria. In more general perspective, our results suggest that the traits connected to bacterial pathogenicity could be indirectly selected as a correlated response by abiotic and biotic factors in environmental reservoirs.
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