ArticleFrontiers in physiology2010
Role of the mitochondrion in programmed necrosis.
Article in Frontiers in physiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
39 citing papers in PubMed.
- Triphenylphosphonium Bolaamphiphile-Liposomes Loaded with Resveratrol and Trolox: Mitochondriotropic Formulations with Therapeutic Potential in Neurodegeneration and Cancer.International journal of nanomedicine · 2026Article
- Review
- PBI-05204, a supercritical CONeoplasia (New York, N.Y.) · 2024Article
- Hybrid non-animal modeling: A mechanistic approach to predict chemical hepatotoxicity.Journal of hazardous materials · 2024Article
- Novel Mitochondria-Targeted Amphiphilic Aminophosphonium Salts and Lipids Nanoparticles: Synthesis, Antitumor Activity and Toxicity.Nanomaterials (Basel, Switzerland) · 2023Article
- The role of mitochondria in rheumatic diseases.Nature reviews. Rheumatology · 2022Review
- The Molecular Quality and Mitochondrial Activity of Porcine Cumulus-Oocyte Complexes Are Affected by Their Exposure to Three Endocrine-Active Compounds under 3D In Vitro Maturation Conditions.International journal of molecular sciences · 2022Article
- Mitochondria signaling pathways in allergic asthma.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2022Review
- Candidalysin triggers epithelial cellular stresses that induce necrotic death.Cellular microbiology · 2021Article
- Farnesyl pyrophosphate is a new danger signal inducing acute cell death.PLoS biology · 2021Article
- mTOR-mediated calcium transients affect cardiac function in ex vivo ischemia-reperfusion injury.Physiological reports · 2021Article
- The Role of Macrophages During Zebrafish Injury and Tissue Regeneration Under Infectious and Non-Infectious Conditions.Frontiers in immunology · 2021Review
- Risuteganib Protects against Hydroquinone-induced Injury in Human RPE Cells.Investigative ophthalmology & visual science · 2020Article
- Natural products and phytochemical nanoformulations targeting mitochondria in oncotherapy: an updated review on resveratrol.Bioscience reports · 2020Review
- Role of Mitofusins and Mitophagy in Life or Death Decisions.Frontiers in cell and developmental biology · 2020Review
- Recent Progress in Mitochondria-Targeted Drug and Drug-Free Agents for Cancer Therapy.Cancers · 2019Review
- PKCγ and PKCε are Differentially Activated and Modulate Neurotoxic Signaling Pathways During Oxygen Glucose Deprivation in Rat Cortical Slices.Neurochemical research · 2019Article
- Article
- Mitofusin2, as a Protective Target in the Liver, Controls the Balance of Apoptosis and Autophagy in Acute-on-Chronic Liver Failure.Frontiers in pharmacology · 2019Article
- Progression of Repair and Injury in Human Liver Slices.International journal of molecular sciences · 2018Article
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
In contrast to the "programmed" nature of apoptosis and autophagy, necrotic cell death has always been believed to be a random, uncontrolled process that leads to the "accidental" death of the cell. This dogma, however, is being challenged and the concept of necrosis also being "programmed" is gaining ground. In particular, mitochondria appear to play a pivotal role in the mediation of programmed necrosis. The purpose of this review, therefore, is to appraise the current concepts regarding the signaling mechanisms of programmed necrosis, with specific attention to the contribution of mitochondria to this process.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.