Evidence map›Paper›PMID 21422993›Full record

ReviewAmerican journal of clinical oncology2013

Merkel cell carcinoma.

Emma Ramahi, Jehee Choi, Clifton D Fuller, Tony Y Eng

Abstract readReview
In one paragraph

Review in American journal of clinical oncology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. The Evolving Treatment Landscape of Merkel Cell Carcinoma.Current treatment options in oncology · 2023
    Review
  4. Article
  5. Merkel Cell Carcinoma Display PIEZO2 Immunoreactivity.Journal of personalized medicine · 2022
    Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. EJNMMI research · 2018
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Emma RamahiDepartment of Radiation Oncology, Cancer Therapy and Research Center, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
Jehee Choi
Clifton D Fuller
Tony Y Eng

Funding

Multidisciplinary Training Program in Human ImagingT32EB000817 · NIBIB · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI CLARKE, GEOFFREY DAVID · 2004 to 2008
$967k
NCI NIH HHS L30 CA136381NIBIB NIH HHS 5T32EB000817-04NIBIB NIH HHS T32 EB000817
6 · The paper itself

Abstract

Merkel cell carcinoma (MCC) is a rare, clinically aggressive cutaneous neuroendocrine neoplasm with a high mortality rate. Though the etiology is not precisely known, Merkel cell polyomavirus DNA has been found recently in a large percentage of MCC tumors. Other suggested risk factors include sun exposure, immunosuppression, and a history of prior malignancy. Work up of patients with MCC most notably includes nodal staging via clinical examination or sentinel lymph node biopsy. The prognosis for most patients with MCC is poor, and the rarity of MCC precludes the prospective, randomized clinical trials necessary to elucidate optimum treatment protocols. Most published data support the use of a multimodality approach centered around surgical excision with negative margins, sentinel lymph node biopsy to establish the presence or absence of nodal metastases, adjuvant radiothearpy to decrease the risk of recurrence, and systemic chemotherapy in the case of widespread disease.

Indexed as

Carcinoma, Merkel CellCombined Modality TherapyHumansPrognosisSkin Neoplasms

Identifiers

PMID21422993
PMCPMC3121923

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.