Evidence map›Paper›PMID 21422804›Full record

SynthesisJournal of endocrinological investigation2011

Thyroid autoimmunity and pre-term delivery: brief review and meta-analysis.

R Negro

Abstract readMeta-AnalysisReview
PubMed Publisher
In one paragraph

Synthesis in Journal of endocrinological investigation, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Management of gestational hypothyroidism: results of a Brazilian survey.Archives of endocrinology and metabolism · 2016
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

R NegroDivision of Endocrinology, V. Fazzi Hospital, Piazza F. Muratore 73100, Lecce, Italy. robnegro@tiscali.it
Ospedale Vito Fazzi · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAbout 10% of women in childbearing age are positive for thyroid antibodies. The presence of such antibodies has been associated with adverse obstetrical outcomes, in particular miscarriage and pre-term delivery, even though the strength of these associations varies widely from one study to another.

aimTo evaluate from the available data of the literature, the association between thyroid autoimmunity and pre-term delivery. MATERIALS AND

methodsMEDLINE, EMBASE, Cochrane Library search from 1990 to 2010. A combination of key words was used to generate 2 subset of citations, one indexing thyroid antibodies and the other indexing pre-term delivery as adverse outcome.

resultsSeven studies, collecting about 23,000 patients were selected. Meta-analysis of the studies showed an association between thyroid autoimmunity and pre-term delivery [odds ratio =1.67 (confidence interval: 1.44- 1.94; p<0.001)].

conclusionsThe results of the meta-analysis confirmed the association between thyroid autoimmunity and pre-term delivery. A cause-effect relationship has to be still clarified and interventional studies are required.

Indexed as

AutoantibodiesAutoimmunityDatabases, FactualFemaleHumansPregnancyPremature BirthThyroid GlandAutoantibodies

Identifiers

PMID21422804
OpenAlexW2071967769

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.