Evidence map›Paper›PMID 21422237›Full record

ArticleJournal of clinical pharmacology2012

Dapsone-associated methemoglobinemia in a patient with slow NAT2*5B haplotype and impaired cytochrome b5 reductase activity.

Mahmoud Abouraya, James C Sacco, Kristie Hayes, Sajeve Thomas, Craig S Kitchens, Lauren A Trepanier

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical pharmacology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Case Study 10: A Case to Investigate Acetyl Transferase Kinetics.Methods in molecular biology (Clifton, N.J.) · 2021
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Mahmoud AbourayaDepartment of Medical Sciences, University of Wisconsin-MadisonDivision of Hematology and Oncology, College of Medicine, University of Florida, Gainesville, Florida.
James C Sacco
Kristie Hayes
Sajeve Thomas
Craig S Kitchens
Lauren A Trepanier
University of Wisconsin–Madison · USUniversity of Florida · US

Funding

UF Clinical and Translational Science AwardUL1TR000064 · NCATS · UNIVERSITY OF FLORIDA · PI NELSON, DAVID R · 2012 to 2014
$12.2M
Comparative Biomedical Sciences Training ProgramT32OD010423 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI Marulasiddappa Suresh · 2012 to 2026
$5.0M
ROLE OF HYDROXYLAMINE REDUCTION IN DRUG HYPERSENSITIVITYR01GM061753 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI TREPANIER, LAUREN A · 2000 to 2010
$2.4M
Comparative Biomedical Sciences Training ProgramT32RR023916 · NCRR · UNIVERSITY OF WISCONSIN-MADISON · PI CZUPRYNSKI, CHARLES JOSEPH · 2007 to 2011
$1.2M
NCATS NIH HHS UL1 TR000064NCRR NIH HHS T32 RR023916NIGMS NIH HHS R01 GM061753NIGMS NIH HHS R01 GM61753NIH HHS T32 OD010423
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AgedAnti-Infective AgentsArylamine N-AcetyltransferaseCytochrome-B(5) ReductaseCytochrome P-450 CYP2C19Cytochromes b5DapsoneHaplotypesHumansMaleMethemoglobinemiaAnti-Infective AgentsArylamine N-AcetyltransferaseCYB5A protein, humanCYB5R3 protein, humanCYP2C19 protein, humanCytochrome-B(5) ReductaseCytochrome P-450 CYP2C19Cytochromes b5DapsoneNAT2 protein, humanadverse drug reactionarylamineMethemoglobinN-acetylation

Identifiers

PMID21422237
PMCPMC3153586
OpenAlexW2007161495

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.