SynthesisJournal of the American Medical Informatics Association : JAMIA2011
Effects of clinical decision-support systems on practitioner performance and patient outcomes: a synthesis of high-quality systematic review findings.
Synthesis in Journal of the American Medical Informatics Association : JAMIA, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 236 papers, 24 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
236 citing papers in PubMed, 24 syntheses or guidelines pooled it.
- Effectiveness of clinical decision support in fall prevention among older adults: A systematic review and meta-analysis.PloS one · 2026Pooled it
- Improving Explainability and Integrability of Medical AI to Promote Health Care Professional Acceptance and Use: Mixed Systematic Review.Journal of medical Internet research · 2025Pooled it
- Designing Clinical Decision Support Systems (CDSS)-A User-Centered Lens of the Design Characteristics, Challenges, and Implications: Systematic Review.Journal of medical Internet research · 2025Pooled it
- Optimizing Clinical Decision Support System Functionality by Leveraging Specific Human-Computer Interaction Elements: Insights From a Systematic Review.JMIR human factors · 2025Pooled it
- The effect of clinical decision support systems on clinical outcomes in acute kidney injury: a systematic review and meta-analysis of randomized controlled trials.Renal failure · 2024Pooled it
- Decision-support tools via mobile devices to improve quality of care in primary healthcare settings.The Cochrane database of systematic reviews · 2021Pooled it
- Association of Clinician Diagnostic Performance With Machine Learning-Based Decision Support Systems: A Systematic Review.JAMA network open · 2021Pooled it
- Optimizing clinical decision support alerts in electronic medical records: a systematic review of reported strategies adopted by hospitals.Journal of the American Medical Informatics Association : JAMIA · 2021Pooled it
- Medication safety alert fatigue may be reduced via interaction design and clinical role tailoring: a systematic review.Journal of the American Medical Informatics Association : JAMIA · 2019Pooled it
- The effect of computerized decision support systems on cardiovascular risk factors: a systematic review and meta-analysis.BMC medical informatics and decision making · 2019Pooled it
- The value of four imaging modalities in diagnosing lymph node involvement in rectal cancer: an overview and adjusted indirect comparison.Clinical and experimental medicine · 2019Pooled it
- An Overview of Systematic Reviews of Chinese Herbal Medicine for Parkinson's Disease.Frontiers in pharmacology · 2019Pooled it
- A systematic review of trials evaluating success factors of interventions with computerised clinical decision support.Implementation science : IS · 2018Pooled it
- Behavioral Economics Interventions in Clinical Decision Support Systems.Yearbook of medical informatics · 2018Pooled it
- Interventions to change the behaviour of health professionals and the organisation of care to promote weight reduction in children and adults with overweight or obesity.The Cochrane database of systematic reviews · 2017Pooled it
- Use of Computerized Clinical Decision Support Systems to Prevent Venous Thromboembolism in Surgical Patients: A Systematic Review and Meta-analysis.JAMA surgery · 2017Pooled it
- Precision diagnosis: a view of the clinical decision support systems (CDSS) landscape through the lens of critical care.Journal of clinical monitoring and computing · 2017Pooled it
- Information Technology-Based Interventions to Improve Drug-Drug Interaction Outcomes: A Systematic Review on Features and Effects.Journal of medical systems · 2017Pooled it
- Computer-Based Clinical Decision Support Systems and Patient-Reported Outcomes: A Systematic Review.The patient · 2015Pooled it
- Reducing diagnostic errors in primary care. A systematic meta-review of computerized diagnostic decision support systems by the LINNEAUS collaboration on patient safety in primary care.The European journal of general practice · 2015Pooled it
176 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo synthesize the literature on clinical decision-support systems' (CDSS) impact on healthcare practitioner performance and patient outcomes.
designLiterature search on Medline, Embase, Inspec, Cinahl, Cochrane/Dare and analysis of high-quality systematic reviews (SRs) on CDSS in hospital settings. Two-stage inclusion procedure: (1) selection of publications on predefined inclusion criteria; (2) independent methodological assessment of preincluded SRs by the 11-item measurement tool, AMSTAR. Inclusion of SRs with AMSTAR score 9 or above. SRs were thereafter rated on level of evidence. Each stage was performed by two independent reviewers.
results17 out of 35 preincluded SRs were of high methodological quality and further analyzed. Evidence that CDSS significantly impacted practitioner performance was found in 52 out of 91 unique studies of the 16 SRs examining this effect (57%). Only 25 out of 82 unique studies of the 16 SRs reported evidence that CDSS positively impacted patient outcomes (30%).
conclusionsFew studies have found any benefits on patient outcomes, though many of these have been too small in sample size or too short in time to reveal clinically important effects. There is significant evidence that CDSS can positively impact healthcare providers' performance with drug ordering and preventive care reminder systems as most clear examples. These outcomes may be explained by the fact that these types of CDSS require a minimum of patient data that are largely available before the advice is (to be) generated: at the time clinicians make the decisions.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.