ArticlePediatrics2011
Risk of asthma in young adults who were born preterm: a Swedish national cohort study.
Article in Pediatrics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 3 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
46 citing papers in PubMed, 3 syntheses or guidelines pooled it, 113 citations in OpenAlex.
- Risk of asthma in preterm infants with bronchopulmonary dysplasia: a systematic review and meta-analysis.World journal of pediatrics : WJP · 2023Pooled it
- Preterm birth and mortality in adulthood: a systematic review.Journal of perinatology : official journal of the California Perinatal Association · 2020Pooled it
- Assessing the social and physical determinants of circumpolar population health.International journal of circumpolar health · 2013Pooled it
- Late childhood and adolescent health outcomes in preterm-born infants during 2004-2012: a population-based cohort study in British Columbia, Canada.Lancet regional health. Americas · 2026Article
- Prevalence and early-life risk factors of asthma in preterm adolescents: a cohort study.Frontiers in pediatrics · 2025Article
- Long-term health outcomes of preterm birth: a narrative review.Frontiers in pediatrics · 2025Review
- Cardiometabolic health in adults born with very low birth weight-a sibling study.Pediatric research · 2024Article
- Accelerated Aging and the Life Course of Individuals Born Preterm.Children (Basel, Switzerland) · 2023Review
- Uncharted territory: a narrative review of parental involvement in decision-making about late preterm and early term delivery.BMC pregnancy and childbirth · 2023Review
- Preterm Birth, Developmental Smoke/Nicotine Exposure, and Life-Long Pulmonary Sequelae.Children (Basel, Switzerland) · 2023Review
- Relation of Maternal Pre-Pregnancy Factors and Childhood Asthma: A Cross-Sectional Survey in Pre-School Children Aged 2-5 Years Old.Medicina (Kaunas, Lithuania) · 2023Article
- Cardiopulmonary Exercise Testing in Childhood in Late Preterms: Comparison to Early Preterms and Term-Born Controls.Journal of personalized medicine · 2022Article
- Time-Specific Factors Influencing the Development of Asthma in Children.Biomedicines · 2022Review
- Perimenstrual Asthma in Adolescents: A Shared Condition in Pediatric and Gynecological Endocrinology.Children (Basel, Switzerland) · 2022Review
- An overview of adult health outcomes after preterm birth.Early human development · 2020Review
- Medication Utilization at School Age for Children Born Preterm.The Journal of pediatrics · 2020Article
- Differences in Compositions of Gut Bacterial Populations and Bacteriophages in 5-11 Year-Olds Born Preterm Compared to Full Term.Frontiers in cellular and infection microbiology · 2020Article
- Persistent metagenomic signatures of early-life hospitalization and antibiotic treatment in the infant gut microbiota and resistome.Nature microbiology · 2019Article
- Article
- Gestational age at birth and mortality from infancy into mid-adulthood: a national cohort study.The Lancet. Child & adolescent health · 2019Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
objectivePreterm birth is associated with asthma-like symptoms in childhood and possibly in adolescence, but the longer-term risk of asthma is unknown and increasingly relevant as larger numbers of these individuals enter adulthood. Our objective was to evaluate whether those who were born preterm are more likely to be prescribed asthma medications in young adulthood than those who were born term. PATIENTS AND
methodsWe conducted a national cohort study of all singleton infants born in Sweden from 1973 through 1979 (n = 622 616), followed to ages 25.5 to 35.0 years to determine whether asthma medications were prescribed in 2005-2007. Asthma medication data were obtained from all outpatient and inpatient pharmacies throughout Sweden. To improve the positive predictive value for asthma, the outcome was defined as prescription of (1) both a β-2 agonist inhalant and a glucocorticoid inhalant or (2) a combination inhalant containing a β-2 agonist and other drugs for obstructive airway diseases.
resultsYoung adults who were born extremely preterm (23-27 weeks' gestation) were 2.4 times more likely (adjusted 95% CI: 1.41-4.06) to be prescribed asthma medications than those who were born term. No association was found between later preterm birth (28-32 or 33-36 weeks' gestation) and asthma medications in young adulthood.
conclusionsThis is the first study with sufficient statistical power to evaluate the risk of asthma beyond adolescence in individuals who were born extremely preterm. The results suggest that extreme preterm birth (23-27 weeks' gestation), but not later preterm birth, is associated with an increased risk of asthma at least into young adulthood.
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Registered trials
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