Evidence map›Paper›PMID 21421925›Full record

ReviewCold Spring Harbor perspectives in biology2011

Organellar calcium buffers.

Daniel Prins, Marek Michalak

Abstract readReview
In one paragraph

Review in Cold Spring Harbor perspectives in biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed.

  1. Increased CaCells · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. The Golgi CaBiophysics reports · 2024
    Article
  9. Article
  10. Review
  11. The ion channels of endomembranes.Physiological reviews · 2024
    Review
  12. Review
  13. IPAntioxidants (Basel, Switzerland) · 2024
    Article
  14. Review
  15. Article
  16. CaBiomedicines · 2023
    Review
  17. Article
  18. Kinetics of the thapsigargin-induced CaFrontiers in physiology · 2023
    Article
  19. Review
  20. Review

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Daniel PrinsDepartment of Biochemistry, School of Molecular and Systems Medicine, University of Alberta, Edmonton, Canada.
Marek Michalak

Funding

Canadian Institutes of Health Research MOP-15291Canadian Institutes of Health Research MOP-15415Canadian Institutes of Health Research MOP-53050
6 · The paper itself

Abstract

Ca(2+) is an important intracellular messenger affecting many diverse processes. In eukaryotic cells, Ca(2+) storage is achieved within specific intracellular organelles, especially the endoplasmic/sarcoplasmic reticulum, in which Ca(2+) is buffered by specific proteins known as Ca(2+) buffers. Ca(2+) buffers are a diverse group of proteins, varying in their affinities and capacities for Ca(2+), but they typically also carry out other functions within the cell. The wide range of organelles containing Ca(2+) and the evidence supporting cross-talk between these organelles suggest the existence of a dynamic network of organellar Ca(2+) signaling, mediated by a variety of organellar Ca(2+) buffers.

Indexed as

Models, BiologicalAnimalsBuffersCalciumCalcium SignalingCalreticulinEndoplasmic Reticulum Chaperone BiPHeat-Shock ProteinsHSP70 Heat-Shock ProteinsHumansMembrane GlycoproteinsMembrane ProteinsMiceOrganellesProtein Disulfide-IsomerasesBuffersCalciumCalreticulinEndoplasmic Reticulum Chaperone BiPendoplasmic reticulum glycoprotein p72glucose-regulated proteinsHeat-Shock ProteinsHSP70 Heat-Shock ProteinsMembrane GlycoproteinsMembrane ProteinsProtein Disulfide-Isomerases

Identifiers

PMID21421925
PMCPMC3039927

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.