Evidence map›Paper›PMID 21421915›Full record

ReviewCold Spring Harbor perspectives in biology2011

Basement membranes: cell scaffoldings and signaling platforms.

Peter D Yurchenco

Open access · bronzeAbstract readReview
In one paragraph

Review in Cold Spring Harbor perspectives in biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 522 papers.

0numbers the graph read from it
0cells of the map it votes in
522citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

522 citing papers in PubMed, 924 citations in OpenAlex.

  1. Article
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  5. Review
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462 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Peter D YurchencoRobert Wood Johnson Medical School, Piscataway, New Jersey 08854, USA. yurchenc@umdnj.edu
Johnson University · US

Funding

Basement Membrane Self-assembly and StructureR37DK036425 · NIDDK · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI YURCHENCO, PETER DANA · 2003 to 2012
$2.9M
NIDDK NIH HHS R37 DK036425NIDDK NIH HHS R37-DK36425
6 · The paper itself

Abstract

Basement membranes are widely distributed extracellular matrices that coat the basal aspect of epithelial and endothelial cells and surround muscle, fat, and Schwann cells. These extracellular matrices, first expressed in early embryogenesis, are self-assembled on competent cell surfaces through binding interactions among laminins, type IV collagens, nidogens, and proteoglycans. They form stabilizing extensions of the plasma membrane that provide cell adhesion and that act as solid-phase agonists. Basement membranes play a role in tissue and organ morphogenesis and help maintain function in the adult. Mutations adversely affecting expression of the different structural components are associated with developmental arrest at different stages as well as postnatal diseases of muscle, nerve, brain, eye, skin, vasculature, and kidney.

Indexed as

AnimalsAxonsBasement MembraneCell AdhesionCell MovementCollagen Type IVDystroglycansHumansIntegrinsKidney GlomerulusLamininMorphogenesisReceptors, Cell SurfaceSignal TransductionCollagen Type IVDystroglycansIntegrinsLamininReceptors, Cell Surface

Identifiers

PMID21421915
PMCPMC3039528
OpenAlexW2121961422

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.